نتایج جستجو برای: bsmi polymorphism and vitamin d receptor gene

تعداد نتایج: 17155683  

Journal: :Immuno 2022

Multiple sclerosis (MS) is a multifactorial neurodegenerative disease. Low levels of vitamin D are risk factor for MS and alterations in the receptor (VDR) might be as well. This study aimed to evaluate whether VDR rs731236 (Taq-I) rs4334089 (HpyCH4V) gene polymorphisms protein expression associated with severity. Vitamin plasma were analyzed group patients. Additional analyses patients differe...

2015
Meng-Yue Niu Lei Wang An-Mu Xie

BACKGROUND The vitamin D receptor (VDR) gene has been identified as a candidate gene for susceptibility to Parkinson's disease (PD), but results from genetic association studies to date are inconsistent. Here, we conducted a meta-analysis of published case-control studies to evaluate the association of the extensively studied VDR ApaI (G/T), BsmI (G/A), FokI (C/T), and TaqI (T/C) gene polymorph...

Journal: :international journal of advanced biological and biomedical research 2014
muhammad haris lucky saeeda baig

objective: the role of vitamin d has soared to a pinnacle in recent years with functions affecting 229 human genes linked to cardiovascular, autoimmune, humoral, pulmonary and neurological diseases. relationship between obesity and vitamin d has not as yet been fully established. the objective of the study was to determine the possible relationship between vitamin d receptor (vdr) gene polymorp...

2018
Zhipeng Pan Mengya Chen Xingxing Hu Hua Wang Jiajia Yang Congjun Zhang Faming Pan Guoping Sun

Background Recent studies have reported the associations between vitamin D receptor (VDR) polymorphisms and colorectal cancer (CRC), but the results were not always consistent. This meta-analysis aims to evaluate whether VDR polymorphisms are associated with CRC susceptibility. Materials And Methods Studies on the associations between VDR polymorphisms and CRC were retrieved from the Web of S...

Journal: :European journal of endocrinology 2001
W Z Ye A F Reis D Dubois-Laforgue C Bellanné-Chantelot J Timsit G Velho

OBJECTIVE Allelic variations in the vitamin D receptor (VDR) gene were reported to modulate insulin secretion in response to glucose. VDR was investigated as a candidate gene for type 2 diabetes mellitus (T2DM). METHOD Four single nucleotide polymorphisms (SNPs) in intron 8 (BsmI, Tru9I, ApaI) and exon 9 (TaqI) of the VDR gene were examined in 309 unrelated French subjects with T2DM and 143 c...

2017
Ieva Martinaityte Rolf Jorde Nina Emaus Anne Elise Eggen Ragnar Martin Joakimsen Elena Kamycheva

BACKGROUND Bone mineral density (BMD) is determined by bone remodeling processes regulated by endocrine, autocrine and genetic mechanisms. Thus, some studies have reported that BMD is associated with single nucleotide polymorphisms (SNPs) associated with vitamin D receptor (VDR), serum 25(OH)D levels and estrogen receptor 1 (ESR1), but without consensus. Therefore, we aimed to map and compare t...

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