Alginate and algal-biomass (Laminaria digitata) beads were prepared by homogeneous Ca ionotropic gelation. In addition, glutaraldehyde-crosslinked poly (ethyleneimine) (PEI) was incorporated into algal beads. The three sorbents were characterized by scanning electron microscopy (SEM) coupled with energy dispersive X-ray analysis (EDX): the sorption occurs in the whole mass of the sorbents. Sorp...

Three-dimensional (3D) bio-printing is a revolutionary technology to reproduce a 3D functional living tissue scaffold in-vitro through controlled layer-by-layer deposition of biomaterials along with high precision positioning of cells. Due to its bio-compatibility, natural hydrogels are commonly considered as the scaffold material. However, the mechanical integrity of a hydrogel material, espec...

Mineralized biomaterials are promising for use in bone tissue engineering. Culturing osteogenic cells in such materials will potentially generate biological bone grafts that may even further augment bone healing. Here, we studied osteogenic differentiation of human mesenchymal stem cells (MSC) in an alginate hydrogel system where the cells were co-immobilized with alkaline phosphatase (ALP) for...

Three-dimensional (3D) printing is an emerging technology for the fabrication of scaffolds to repair/replace damaged tissue/organs in tissue engineering. This paper presents our study on 3D printed alginate scaffolds treated with phosphate buffered saline (PBS) and polyethyleneimine (PEI) coating and their impacts on the surface morphology and cellular response of the printed scaffolds. In our ...

Background: Biosurfactants are derived from microbes, plants, and animals. Acinetobacter junii B6 is a lipopeptide biosurfactant producer previously investigated for its structure, physicochemical, product aggregation properties. Objectives: In this study, we optimized the bioencapsulation of A. in calcium alginate hydrogel. Methods: was encapsulated using The formulation hydrogel full factoria...

In this study, a hybrid system consisting of 3D printed polycaprolactone (PCL) filled with hydrogel was developed as an application for reconstruction of long bone defects, which are innately difficult to repair due to large missing segments of bone. A 3D printed gyroid scaffold of PCL allowed a larger amount of hydrogel to be loaded within the scaffolds as compared to 3D printed mesh and honey...

In article number 2006759, Hyung Joon Cha, Joonwon Kim, and co-workers develop an optical-fiber-integrated microfluidic device that can continuously form hydrogel microfibers via in situ photo-crosslinking extreme endovascular environments. The are based on a double-crosslinked alginate employs the dityrosine bond. This with is attractive strategy to fill aneurysms effectively.

We report herein a simple system for continuously synthesizing complex Ca-alginate fibers using a uniformdepth, co-flowing microchannel. The continuous flow of sodium alginate (NaA) solution is gradually gelled in the microchannel by the diffusion of Ca ions from the outer gelation solutions. Introduction of thin buffer layers between the NaA and the gelation solutions could regulate the gelati...