نتایج جستجو برای: bacillus anthracis sterne 34f2
تعداد نتایج: 56765 فیلتر نتایج به سال:
Towards the goal of developing a real-time monitoring device for microorganisms, we demonstrate the use of microcantilevers as resonant mass sensors for detection of Bacillus anthracis Sterne spores in air and liquid. The detection scheme was based on measuring resonant frequency decrease driven by thermally induced oscillations, as a result of the added mass of the spores with the use of a las...
The nontoxic mutant lethal factor (mLF; which has the E687C substitution) and functional protective antigen (PA63) of Bacillus anthracis were evaluated for their use as mucosal vaccines against anthrax in A/J mice. Intranasal vaccination of three doses of 30 microg of mLF or 60 microg of PA63 elicited significant serum and mucosal antibody responses, with anthrax lethal toxin-neutralizing titer...
Bacillus anthracis are aerobic or facultatively anaerobic Gram-positive, nonmotile rods measuring 1.0 μm wide by 3.0–5.0 μm long. Under adverse conditions, B. anthracis form highly resistant endospores (Figure 1). These are found in soil at sites where infected animals previously died. Interest in the pathogenesis, immunity, and vaccine development for anthrax was heightened by the deliberate c...
BACKGROUND In the last ten years, bioterrorism has become a serious threat and challenge to public health worldwide. Pulmonary anthrax caused by airborne Bacillus anthracis spores is a life-threatening disease often refractory to antimicrobial therapy. Inhaled spores germinate into vegetative forms that elaborate an anti-phagocytic capsule along with potent exotoxins which disrupt the signaling...
The identification of Bacillus anthracis involves its differentiation from other aerobic sporeformers, particularly Bacillus cereus. Smith et al. (1952), in a study of aerobic sporeforming bacteria, concluded that B. anthracis is a pathogenic variety of B. cereus. They also stated that strains of B. anthracis which had lost their virulence could not be differentiated from B. cereus. This appare...
AIMS To better understand the parameters that govern spore dissemination after lung exposure using in vitro cell systems. METHODS AND RESULTS We evaluated the kinetics of uptake, germination and proliferation of Bacillus anthracis Sterne spores in association with human primary lung epithelial cells, Calu-3 and A549 cell lines. We also analysed the influence of various cell culture medium for...
BACKGROUND Previous studies in a murine cutaneous anthrax model have demonstrated that hairless and haired HRS/J mice are extremely resistant to Bacillus anthracis. Because these mice are relatively thymus deficient, we used C57BL/6 athymic nude and euthymic mice to evaluate the relationship between T cell deficiency and this heightened resistance. METHODS Animals were epicutaneously inoculat...
Live spore Sterne 34F-2 strain of Bacillus anthracis vaccine is being used to control anthrax disease in Bangladesh. After produced this Livestock Research Institute (LRI) under the Department Services (DLS), it distributed at farmers level through district and Upazila Offices. In these distribution pathways, has been transported stored for a few days each station. The present study was carried...
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