Objective: The Achillea species have been used to treat various ailments due its anti-inflammatory, hemostatic, spasmolytic and cholagogue effects in the Turkish traditional medicine. However, there is no biological activity studies on some except for well-knowns. This work aimed determine antioxidant, antimicrobial cytotoxic activities of crude ethanolic extracts fractions sintenisii using vit...

Cervical cancer as one of the major malignant tumors seriously threatens women's health. More than 270,000 women die cervical each year. Warangalone is an isoflavone compound isolated from Cudrania tricuspidata with excellent antitumor activity. In this research, we investigated molecular mechanism warangalone-induced apoptosis in HeLa cells. The results show that warangalone can selectively an...

Pancreatic cancer is a kind of malignant tumor with high mortality rate. Early operation and late chemoradiotherapy are the treatment criteria, but prognosis still poor. Berberine, an alkaloid compound present in many herbal plants, capable inducing oxidative DNA damage downregulating homologous recombination repair (HRR) cells. Poly (ADP ribose) polymerase-1 (PARP-1) sensor key roles repair. I...

Group B Streptococcus (GBS) is a pathogen that has developed some strategies to resist host immune defenses. Because phagocytic killing is an important pathogenetic mechanism for bacteria, we investigated whether GBS induces apoptosis in murine macrophages. GBS type III strain COH31 r/s (GBS-III) first causes a defect in cell membrane permeability, then at 24 h, apoptosis. Apoptosis was confirm...

objective(s):pharmacological studies showed that the extracts of jin yin hua and its active constituents have lipid lowering, antipyretic, hepatoprotective, cytoprotective, antimicrobial, antibiotic, antioxidative, antiviral, and anti-inflammatory effects. the purpose of the present study was to investigate the protective effects of caffeoylquinic acids (cqas) from jin yin hua against hydrogen ...

objective(s):  chlorpyrifos (cp) is a broad-spectrum organophosphorus pesticide used extensively in agricultural and domestic pest control, accounting for 50% of the global insecticidal use. in the present study, protective effects of two selenium-enriched strong antioxidative medicines imod and angipars were examined in human lymphocytes treated with cp in vitro. materials and methods: isolate...