Molecular hydrogen (H 2) has recently been recognized as a potential novel therapeutic agent in biomedicine. Initially proposed to be a possible treatment for certain types of neuromuscular disorders, cardio-metabolic diseases and cancer, H 2 improved clinical end-points and surrogate markers in several clinical trials, mainly acting as an anti-inflammatory agent and powerful antioxidant. In th...

With the accelerated aging of human society Alzheimer's disease (AD) has become one of the most threatening diseases in the elderly. However, there is no efficient therapeutic agent to combat AD. Berberine is a natural isoquinoline alkaloid that possesses a wide range of pharmacological effects. In the present paper, we review the multiple activities of berberine, including antioxidant, acetylc...

From long time, scientists are looking for natural biomolecules in order to discover new pharmaceutical agents. Therefore polysaccharides which are natural molecules from several biotopes (microbial, plant, algae, fungi, animals, and insects) constitute a very large potential of application for medical treatment. Among them, chitosan a deacetylated form of chitin (one of the most abundant polys...

The essential oil composition of Thymus vulgaris L. and Rosmarinus officinalis L. endemic to France were determined by GC and GC-MS. Oils were assessed for their cytotoxic, antioxidant and antimicrobial activity. 31 and 37 different compounds were identified representing 99.64% and 99.38% of the thyme and rosemary oils respectively, where oxygenated monoterpenes constituted the main chemical cl...

Melatonin is known to have a multiple biological action potential. Melatonin and several of its metabolites have been shown to act as an antioxidant and cytoprotective agent by reducing the oxidative stress by acting as a free radical scavenger [1], and also by activating several antioxidant systems [2]. Melatonin is originally defined as an agent which reduces lipid peroxidation and scavenges ...

lated to play an important role in the pathogenesis of acute gastric mucosal injury induced by ischemia-reperfusion, stress, ethanol and anti-inflammatory drugs in rats. Furthermore, it has been suggested that free radicals generated by neutrophils may be important factors in delaying the healing of acetic acid-induced chronic gastric ulcers in these animals. It has been reported that polaprezi...

The catechin (-)-epigallocatechin-3-gallate (EGCG) exhibits high antioxidant activity and it has been reported to provide protection of the skin against damage induced by solar UV radiation. However, EGCG is highly unstable under sunlight. The present study aimed to compare the effectiveness of the co-antioxidant agents vitamin E, butylated hydroxytoluene, vitamin C and a-lipoic acid for their ...

This paper describes the investigative report on phytochemical constituents and antioxidant activity of two plants, Diospyros malabarica and Gardenia jasminoides for their potential as therapeutics. Diseases like cancer, rheumatoid arthritis, liver diseases and atherosclerosis as well as in degenerative processes associated with ageing are the consequence of various metabolic activities in our ...

The objective of the present study was to evaluate the antioxidant activity, antitumor effect, and antiaging property of proanthocyanidins from Kunlun Chrysanthemum flowers (PKCF) grown in Xinjiang. In vitro antioxidant experiments results showed that the total antioxidant activity and the scavenging capacity of hydroxyl radicals ((•)OH) and 1,1-diphenyl-2-picrylhydrazyl (DPPH(•)) radicals incr...