Experimental data indicate that nitric oxide (NO) may play a role in the pathophysiology of epilepsy. It is also possible that NO-mediated events are involved in the expression of the anticonvulsant action of some antiepileptics. The aim of this review was to assemble current literature data on the role of NO in the anticonvulsant action of antiepileptic drugs (AEDs). The influence of various N...

SECTION 1 A 14-year-old boy presented for admission after repeated episodes of lethargy and cognitive changes. He had a history of childhood absence epilepsy that had resolved with antiepileptics discontinued 1 year prior to presentation. Two months prior to admission, the patient had a febrile illness with headache and diarrhea that lasted a few days. It was attributed to a nonspecific viral i...

True and psychogenic nonepileptic seizures (PNES) go hand in hand. One colors the picture of other. Although it is thought that children carry lower risk for PNES than adults, this may represent the under-diagnosis of this condition in childhood due to few studies on this specific topic. Again, true seizure can be misdiagnosed by dramatic and varied manifestations appearing as psychological phe...

ee front matter & 2005 urobgyn.2005.05.004 ng author. ess: [email protected] ( TE D PR O Summary Many women use alternatives to hormone therapy believing them to be safer and ‘more natural’, especially following the current controversies regarding hormone replacement therapy. The choice of treatments is confusing, and unlike conventional medicines, not much is known about their active ingredients...

Fibromyalgia has a distinct pathophysiology involving central amplification of peripheral sensory signals. Core symptoms are chronic widespread pain, fatigue, and sleep disturbance. Most patients with fibromyalgia have muscle pain and tenderness, forgetfulness or problems concentrating, and significant functional limitations. Fibromyalgia is diagnosed using an updated set of clinical criteria t...

s, 18th InternationalEpilepsy Congress, p. 90, New Delhi, India, 1989a.KALVIAINEN, R., SIvENIUS, J., YLINEN, A., AND RIEKKINEN, P. J.: A double-blind study of gabapentin in treatment of partial seizures. Epilepsia, 30: 661, l989b.KAMEI, C., OKA, M., MASUDA, Y., YOSHIDA, K., AND SHIMIZU, M.: Effectsof 3-sulfamoylmethyl-1,2-benzisoxazole(AD-8l0) and some antiepileptics on ...

BACKGROUND The aim of the study was to examine effects of an acute and chronic treatment with trazodone, a serotonin antagonist and reuptake inhibitor (SARI), on the protective activity of four classical antiepileptic drugs provided in the maximal electroshock test in mice. METHODS Electroconvulsions were produced in mice by means of an alternating current (50 Hz, 25 mA, 0.2 s) and delivered ...

BACKGROUND Estimates of risk of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) associated with some antiepileptic drugs (AEDs) have used denominators based on the number of prescriptions or daily doses. Because the risk of SJS is highest in new users of drugs, the use of denominators reflective of all users can lead to low estimates of risk associated with drugs. In this st...

Posterior reversible encephalopathy syndrome (PRES) is a clinicoradiological that being increasingly recognized due to the advancements in brain imaging, specifically MRI. This characterized by symptoms including, but not limited to, headache, seizures, altered mental status, and vision loss. There are various underlying etiologies which lead PRES occurrence; etiology of focus this report preec...