OBJECTIVES Umbelliprenin is a prenyloxy-coumarin with pharmacologically polyvalent activity. Several studies have shown Several studies have been shown its anti-inflammatory, anti-tumor, antioxidant, and antigenotoxic activities. However, the exact mechanism of action of this compound on the immune response has not yet been shown. Here, we investigated umbelliprenin effects on the predominance ...

Background: Perovskia abrotanoides is small kind of lamiaceae family that find in iran and some neighboring countries by endemic. Objective: Because The effect of anti-bacterial and anti-fungal medical plant extract on bacteria and fungi and determine the Minimal Inhibitory Concentration (MIC) has not been done so present study follow the above aim. Methodes: In this study by using 80% methan...

The photoinitiated substitution reactions of anti-7-bromobenzonorbornadiene (5), its syn isomer 6, exo-anti-13-bromobenzocyclobutanorbornene (7), syn-7-bromonorbornene (8) and bromonorbornane (9) with Me(3)Sn(-) and Ph(2)P(-) anions, in liquid ammonia, are here informed to occur with good yields of substitution. The stereochemical outcome is discussed in terms of calculations with the B3LYP fun...

Pharmacognostical investigations were carried out on the Erythrina indica leaves, followed by phytochemical investigation. On the methanolic extract of leaves, TLC was performed and indole alkaloids were identified with selected solvent system. The UV analysis was also performed on the components confirming the presence of the indole nucleus. Anti-inflammatory activity was carried out on albino...

Secreted by the adipose tissue, adiponectin is an adipokine with unique anti-diabetic, anti-obesity and antiatherosclerosis properties. Adiponectin has been proposed as a drug target for treating obesity-related diseases and many existing drugs have been found to regulate circulating adiponectin levels in humans. The initial goal of this study was to characterize the binding of potential ligand...

The new anti-cancer and water-soluble curcumin derivatives have been synthesized solvent-freely by functionalizing the phenolic group of with various NH compounds to increase water solubility cancerous properties. biological applications drugs investigated against highly potent HepG2 carcinoma cell line. studies showed that could be used in low concentrations (µM/l<1) avoid anti-apoptoti...

Phytochemical investigation of the aerial parts of Euphorbia erythradenia Bioss. (Euphorbiaceae), one of Iranian endemic Euphorbias, with particular attention to triterpene constituents, using methanol solvent extraction was carried out. Five known triterpenes, including four cycloartanes and oleanolic acid, were isolated for the first time and identified using NMR and Mass techniques. Anti HIV...

Nano-TiO2 sol and finishing agent was prepared by sol-gel method, during which tetrabutyl titanate was used as precursor and ethanol was used as solvent. The agent was penetrated into polyester fabric through a padding method, the anti-ultraviolet performance of the fabric was analyzed and the external morphology was carefully studied afterward. The results showed that indicated that the Nano-T...