Bu araştırmada Osmanlı Devleti’nin Gerileme dönemi içinde olan 1788 – 1821 yılları arasında Yanya Valisi olarak görev yapan Tepedelenli Ali Paşa’nın üç romandaki tezahürü incelenir. Bunlar, Ahmet Mithat Efendi’nin Arnavutlar Solyotlar, İsmail Kadare’nin İbret Taşı (Kamarja e Turpit) ve Alexandre Dumas’ın Paşa (Ali Pacha) adlı romanlarıdır. Bahsi geçen tarihî şahsiyetin sırasıyla Türk, Arnavut F...

This article examines the significance of and motives behind projection a distinctively Islamic image King Faruq Egypt in years that followed his ascent to Throne 1936. It argues creation persona al-malik al-salih (the righteous king) was one aspect strategy developed by Ali Mahir Pasha (Prime Minister then Head Royal Diwan) safeguard monarchy an era mass politics. The campaign, however, took o...

142 Double-Blind, Randomized Trial of Alternative Letrozole Dosing Regimens in Postmenopausal Women with Increased Breast Cancer Risk Ana Maria López, Sandhya Pruthi, Judy C. Boughey, Marjorie Perloff, Chiu-Hsieh Hsu, Julie E. Lang, Michele Ley, Denise Frank, Josephine A. Taverna, and H-H. Sherry Chow 149 Relationship of Terminal Duct Lobular Unit Involution of the Breast with Area and Volume M...

DGCR8/Pasha is an essential cofactor for Drosha, a nuclear RNase III that cleaves the local hairpin structures embedded in long primary microRNA transcripts (pri-miRNAs) in eukaryotes. Although our knowledge of pri-miRNA processing has significantly advanced in recent years, the precise role of DGCR8 in this pathway remains unclear. In our present study, we dissect the domains in DGCR8 that con...

The Drosha-DGCR8 complex, also known as Microprocessor, is essential for microRNA (miRNA) maturation. Drosha functions as the catalytic subunit, while DGCR8 (also known as Pasha) recognizes the RNA substrate. Although the action mechanism of this complex has been intensively studied, it remains unclear how Drosha and DGCR8 are regulated and if these proteins have any additional role(s) apart fr...

museum of foods, drugs and instruments in which by far the most prominent and artistic exhibit was that of Messrs. Burroughs, Wellcome & Co., with its offshoots upon which the Fairchild Digestive Ferments and Wyeth Beef Juice were shown. The height of perfection to which the manufacture of "tabloids" has been carried was well shown by the examples exhibited, including Cascara, Quinine, Voice, B...