introduction: laser phototherapy is used for the treatment of chemotherapy-induced oral mucositis in patients with leukemia, although there are limited data supporting the safety of this method. this study aimed to evaluate the effect of different doses of low-level laser on proliferation of acute myeloid leukemia (aml) cell line (kg-1a) in vitro. methods: a plastic flask containing 5,000,000 k...

conclusions in iran, hsct has been successfully adapted in routine clinical care. recently, new methods such as double cord blood and haploidentical transplantation have been used to treat many life-threatening diseases. results about 78.2% of the patients (2530 of 3237) remained alive between one to 211 months after stem cell transplantation. nearly, 21.8% (707) of our patients died after stem...

introduction campylobacter jejuni is a slender, motile, non-spore-forming, helical-shaped, gram-negative bacterium. it is one of the most common causes of human gastroenteritis in the world. the aim of this study was to present a patient with acute lymphocytic leukemia (all), who was infected with campylobacter jejuni. conclusions c. jejuni should be considered in the differential diagnosis as ...

background: pediatric patients on chemotherapy are vulnerable to invasive fungal infection especially candida spices. resistance to antifungal agents has increased in candida spp., especially in non-albicans species. this study aims to assess the susceptibility of candida spp. strains isolated from children with acute leukemia less than 18 years. materials and methods: this prospective cross-se...

Objective: This study aims to determine the relationship among demographic, clinical characteristics, and psychosocial factors related salivary cortisol in children with leukemia. Methods: research was a descriptive cross-sectional design. The sample leukemia Dr. Sardjito General Hospital Yogyakarta from January February 2018 size 30 respondents who had met inclusion criteria, aged 6-18 years, ...

NUDT15 genetic variants and 6-mercaptopurine intolerance in pediatric acute lymphoblastic leukemia: an updated review

background: interaction between killer cell immunoglobulin-like receptors (kir) and human leukocyte antigen (hla) class i molecules is important for regulation of natural killer (nk) cell function. objective: the aim of this study was to investigate the impact of compound kir-hla genotype on susceptibility to acute leukemia. methods: cohorts of iranian patients with acute myeloid leukemia (aml;...

endocarditis due to aspergillus infection is a rare complication in patients with hematological malignancies. here, we present a case of aspergillus endocarditis in a patient with acute myeloid leukemia (aml) successfully treated with antifungal therapy and surgical treatment. the patient was a 51 years old male, a known case of aml who was admitted to our medical center for evacuating his valv...

backgroundfor using of complementary and alternative medicine methods (cam) in the leukemia pediatrics than other types of cancer, we have two great challenges; first challenge is their safety and risks and second challenge is study gaps in this field. regarding to these challenges, this study is a narrative review of some cam methods in the leukemia pediatrics from the perspective of their saf...

1. dept. of hematology, oncology, kermanshah university of medical sciences, kermanshah, iran 2. medical biology research center, kermanshah university of medical sciences, kermanshah, iran 3. students research committee, kermanshah university of medical sciences, kermanshah, iran     corresponding author: masoud sadeghi, msc; degree in biochemistry tel: (+91) 8338428221 email: sadeghi_mbrc@yah...