Background: Monte Carlo determination of TG-43 brachytherapy dosimetry parameters and dose distribution calculation for 131Cs source model CS-1 are presented in this study. Materials and Methods: The dose distribution was calculated around the 131Cs Model CS-1 located in the center of 30 cm ×30 cm ×30 cm water, and soft tissue phantoms cube using MCNP code by Monte Carlo method. The percentage ...

Background: Ionizing radiation irradiated from iodine-131 can induce DNA damage and cell death. The cellular DNA damage is the cause of mutation and cancer. The micronucleus assay in polychromatic erythrocytes was applied to assess the radio-protective effect of Turmeric extract on genotoxic potential of iodine therapy. Materials and Methods: Thirty six male albino rats were randomly divided in...

Background: Palladium-103 (103Pd) is a brachytherapy source for cancer treatment. The Monte Carlo codes are usually applied for dose distribution and effect of shieldings. Monte Carlo calculation of dose distribution in water phantom due to a MED3633 103Pd source is presented in this work. Materials and Methods: The dose distribution around the 103Pd Model MED3633 located in the center of 30×...

BACKGROUND In radiotherapy treatment planning, intravenous administration of an iodine-based contrast agent during computed tomography (CT) improves the accuracy of delineating target volumes. However, increased tissue attenuation resulting from the high atomic number of iodine may result in erroneous dose calculations because the contrast agent is absent during the actual procedure. The purpos...

The glycoprotein purified from the mycelium extract of Tremella fuciformis was marked with iodine through the iodine substitution reaction. The content of iodine, which is indicative of the amount of the marked tremella glycoprotein (ITG), was detected with Inductively coupled plasma mass spectrometry (ICP-MS). The method was found to be stable, sensitive, and accurate at detecting the content ...

UNLABELLED The ability to estimate absorbed doses in experimental animals to which radiolabeled material has been administered may be important in explaining and controlling potential radiation toxicity observed during preclinical trials. Most previously reported models for establishing doses to small animals have been stylized and mathematically based. This study establishes dose factors for i...

Bayesian hierarchical models are built to fit multiple health endpoints from a dose-response study of a toxic chemical, perchlorate. Perchlorate exposure results in iodine uptake inhibition in the thyroid, with health effects manifested by changes in blood hormone concentrations and histopathological effects on the thyroid. We propose linked empirical models to fit blood hormone concentration a...