نتایج جستجو برای: 549 cell line

تعداد نتایج: 1970969  

Journal: :Journal of Investigative Dermatology 2023

Patients who receive stem cell transplantation (SCT) can develop cutaneous eruptions with systemic involvement such as graft versus host disease (GVHD), drug hypersensitivity syndrome (DIHS), or viral exanthema. These conditions often have overlapping clinical and laboratory presentations may be associated risk factors reactivation medications. In this study, we evaluated the incidence, present...

Journal: :Cancer letters 2008
Song-Shei Lin Hsuan-Pang Huang Jai-Sing Yang Jeng-Yuan Wu Te-Chun Hsia Chin-Chung Lin Cheng-Wen Lin Chao-Lin Kuo W Gibson Wood Jing-Gung Chung

Curcumin, a major component of the Curcuma species, is known to have antioxidant, anti-inflammatory properties and induce apoptosis of cancer cells, however, the precise molecular mechanisms of apoptosis in vitro are unclear. In this study, we showed that curcumin, a plant product containing the phenolic phytochemical, caused DNA damage and endoplasmic reticulum (ER) stress and mitochondrial-de...

2008
Nathan T. Ihle Robert Lemos David Schwartz Junghwan Oh Robert J. Halter Peter Wipf Lynn Kirkpatrick Garth Powis

The phosphatidylinositol 3-kinase (PI3K)/Akt signaling cascade is an important component of the insulin signaling in normal tissues leading to glucose uptake and homeostasis and for cell survival signaling in cancer cells. Hyperglycemia is an on-target side effect of many inhibitors of PI3K/Akt signaling including the specific PI3K inhibitor PX-866. The peroxisome proliferator-activated recepto...

2008
Lecia J. Gresham Jetaime Ross Ernest B. Izevbigie

Evidence suggests that most chemotherapeutic agents are less effective as treatment in patients with estrogen receptor-negative (ER-) breast carcinomas compared to those with estrogen receptor-positive (ER+) breast carcinomas. Moreover, African American Women (AAW) is disproportionately diagnosed with ER- breast cancer compared to their white counterparts. Novel therapies effective against ER- ...

Journal: :International journal of clinical and experimental pathology 2015
Bao-Yi Zhang Yan-Ming Wang Hai Gong Hui Zhao Xiao-Yan Lv Guang-Hui Yuan Shao-Rong Han

The development of novel antitumor drugs for the treatment of non-small cell lung carcinoma NSCLC is imperative in order to improve the efficacy of lung cancer therapy and prognosis. In the current study, we demonstrated the antitumor activity of isorhamnetin and its combinations with cisplatin and carboplatin against A-549 lung cancer cells. In order to assess the anticancer enhancing effect o...

Journal: :Journal of clinical microbiology 2002
Yung T Huang Paul Yam Huimin Yan Yan Sun

Decay-accelerating factor (DAF) has been reported to be a cellular receptor for several enteroviruses. Buffalo green monkey kidney (BGMK) cells expressing human DAF (BGMK-hDAF cells) showed increased susceptibility and sensitivity to several types of enteroviruses compared to wild-type BGMK cells. When 17 frozen positive clinical samples were tested, BGMK cells detected 8 and BGMK-hDAF cells de...

Journal: :Cancer research 1987
K R Bray J E Koda P K Gaur

CA-549 is a circulating breast cancer-associated antigen that reacts with monoclonal antibody BC4E 549. Biochemical characterization of CA-549 revealed that it is an acidic (isoelectric point 5.2) glycoprotein that exhibits two bands by sodium dodecyl sulfate-polyacrylamide gel electrophoresis under reducing conditions of apparent molecular weights of 400,000 and 512,000. Immunohistochemical st...

M. Hamzeloo-Moghadam M. Mosaddegh S. Esmaeili S. Ghaffari

Background and objectives: Cancer is a public health problem all over the world. Herbal medicines have a vital role in the prevention and treatment of cancer and large numbers of plants and their isolated constituents have shown potential anticancer activity. Methods: Twenty seven medicinal plants from southern Iran provinces have been extracted with methanol and screened for their cytotoxic ac...

2014
Masato Terashima Kazuko Sakai Yosuke Togashi Hidetoshi Hayashi Marco A De Velasco Junji Tsurutani Kazuto Nishio

Triple-negative breast cancer (TNBC) is associated with a higher incidence of recurrence and distant metastasis and a poor prognosis, whereas effective treatment strategies remain to be established. Finding an effective treatment for TNBC has become imperative. We examined the effect of the combination of S-1 (or 5-FU in an in vitro study) and eribulin in TNBC cell lines. The in vitro effect of...

Journal: :iranian biomedical journal 0
سعید قوامی saeid ghavami محمد هاشمی mohammad hashemi فاطمه کرمی تهرانی fatemeh karami tehrani بیژن فرزامی bijan farzami محمد تقی خانی mohammad taghikhani

zn (ii) is an important regulator of caspase-3, as well as an antioxidant, microtubule stabilizer, growth cofactor, and anti-inflammatory agent. over the past 30 years, many researchers have demonstrated the important role of zn (ii) in a variety of physiological processes, including growth and development, maintenance and priming of the immune system, and in tissue repair and regeneration. in ...

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