نتایج جستجو برای: 1 glycoprotein b

تعداد نتایج: 3364606  

Journal: :Journal of clinical microbiology 2004
Catherine Gaudy Alain Moreau Sylvie Brunet Jean-Michel Descamps Pascale Deleplanque Denys Brand Francis Barin

We report a case of human immunodeficiency virus (HIV) type 1 infection not detected by a highly sensitive combined antigen-antibody assay. The virus was a subtype B strain harboring a unique sequence within the immunodominant epitope of the transmembrane glycoprotein. Immunochemical analysis indicated that this sequence was probably responsible for the failure to detect HIV antibodies.

Journal: :Journal of neurovirology 1998
V Sivadon P Lebon F Rozenberg

The factors which cause herpes simplex encephalitis (HSE) to occur among herpes simplex virus type 1 (HSV-1) infected humans are not understood. In experimental models, HSV-1 neuroinvasiveness is influenced by amino acid changes in HSV glycoproteins D (gD) or B (gB), which are essential to the virus infectivity and to the induction of host immune responses. To test the possible involvement of t...

2017
Simone Haeberlein Katja Obieglo Arifa Ozir-Fazalalikhan Mathilde A M Chayé Henrike Veninga Luciën E P M van der Vlugt Astrid Voskamp Louis Boon Joke M M den Haan Lotte B Westerhof Ruud H P Wilbers Arjen Schots Gabriele Schramm Cornelis H Hokke Hermelijn H Smits

Infection with the helminth Schistosoma (S.) mansoni drives the development of interleukin (IL)-10-producing regulatory B (Breg) cells in mice and man, which have the capacity to reduce experimental allergic airway inflammation and are thus of high therapeutic interest. However, both the involved antigen and cellular mechanisms that drive Breg cell development remain to be elucidated. Therefore...

Journal: :acta medica iranica 0
shabnam yazdian department of toxicology & pharmacology, faculty of pharmacy, tehran university of medical sciences, tehran, iran. najmeh fahham department of pharmacology, iran pasteur institute, tehran, iran. mohammad hossein ghahremani department of toxicology & pharmacology, faculty of pharmacy, tehran university of medical sciences, tehran, iran. monireh afzali virtual school, tehran university of medical sciences, tehran, iran. narges farsandaj department of toxicology & pharmacology, faculty of pharmacy, tehran university of medical sciences, tehran, iran. melody vatankhah department of biology, college of science, university of tehran, tehran, iran.

there is a great concern about the effect of propoxur, as one of the more common n-methyl carbamate pesticides, on human health due to its extensive use in agricultural and non-agricultural applications. caco-2 cells became resistant to propoxur, and the resistance was confirmed through mtt assay. then the cell membrane integrity and p-glycoprotein expression were measured by ldh assay and west...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2016
Tzviya Zeev-Ben-Mordehai Daven Vasishtan Anna Hernández Durán Benjamin Vollmer Paul White Arun Prasad Pandurangan C Alistair Siebert Maya Topf Kay Grünewald

Many viruses are enveloped by a lipid bilayer acquired during assembly, which is typically studded with one or two types of glycoproteins. These viral surface proteins act as the primary interface between the virus and the host. Entry of enveloped viruses relies on specialized fusogen proteins to help merge the virus membrane with the host membrane. In the multicomponent herpesvirus fusion mach...

Journal: :The Journal of infectious diseases 2009
Nina M van Sorge Darin Quach Michael A Gurney Paul M Sullam Victor Nizet Kelly S Doran

BACKGROUND Group B Streptococcus (GBS) is the leading cause of bacterial meningitis in newborn infants. Because GBS is able to invade, survive, and cross the blood-brain barrier, we sought to identify surface-expressed virulence factors that contribute to blood-brain barrier penetration and the pathogenesis of meningitis. METHODS Targeted deletion and insertional mutants were generated in dif...

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