conclusions it was the first report on the blactx-m-15 gene emergence in clinical enterobacter spp. in iran. the current study demonstrated the predominant presence of the gene encoding ctx-m-15 among esbl producing enterobacter spp. commonly with a large plasmid, in the setting. background enterobacter spp. is increasingly recognized as an important nosocomial pathogen and implicated in many e...

OXA-48 is an emerging class D carbapenemase originally identified in isolates from Turkey (14) and subsequently detected in several European and north African countries (10). Klebsiella pneumoniae is the most common host for OXA-48, but the enzyme has also been detected in Escherichia coli and Enterobacter cloacae (10). The blaOXA-48 gene is carried by the composite transposon Tn1999 or a varia...

Introduction: There are limited treatments options for carbapenem resistant Enterobacteriaceae (CRE) species and especially colistin, fosfomycin and tigecyclin are used for treatment. Therefore, in this study, we aimed for determining the rates of antibiotic susceptibility against colisting, fosfomycin and tigecyclin in CRE isolates with microdilution method. Material method: In our study, a to...

Providencia is a genus of Gram-negative and non-spore forming bacteria belonging to the family Morganellaceae, which causes opportunistic infections in humans. Of 10 species identified date, three, P. alcalifaciens, rettgeri stuartii, are clinically important. alcalifaciens diarrhea, including outbreaks arising from food-borne infections, stuartii have been found cause hospital acquired urinary...

Previously evidence was presented for the existence of a new enzyme, L-xylulokinase, which is instrumental in the degradation of L-xylulose by Aerobacter aerogenes (1). This enzyme is of interest because it initiates a pathway for the metabolism of L-xylulose which is different from that known to occur in mammals (2). This paper describes the purification and properties of Lxylulokinase from L-...

BACKGROUND Extended-spectrum ß-lactamase-producing Enterobacteriaceae (ESBL-PE) are increasingly reported as pathogens in urinary tract infections (UTIs). However, in Sri Lanka, the clinical and molecular epidemiology of ESBL-PE implicated in UTIs has not been well described. MATERIALS AND METHODS We conducted prospective, laboratory-based surveillance from October to December 2013 at a terti...

BACKGROUND Pseudomonas aeruginosais a frequent nosocomial pathogen that causes severe diseases in many settings. Carbapenems, including meropenem and imipenem, are effective antibiotics against this organism. However, the use of carbapenems has been hampered by the emergence of strains resistant to carbapenemsvia different mechanisms such as the production of metallo-β-lactamases (MBLs), which ...

The availability of safe and pristine water is a global challenge when large numbers of natural and anthropogenic water resources are being depleted with faster rate. The remaining water resources are severely contaminated with various kinds of contaminants including microorganisms. Enterobacter is one of the fecal coliform bacteria of family Enterobacteriaceae. Enterobacter was earlier used as...

BACKGROUND AND OBJECTIVES Resistance among bacterial isolates is the leading cause of increased mortality and morbidity worldwide. Carbapenems once thought to be effective are becoming ineffective mostly due to the emergence of carbapenemase. This study was designed to determine in vitro efficacy of Modified Hodge test for detection of carbapenemase production in Gram negative rods. MATERIAL ...