We have previously shown that a decreased level of phosphatidylglycerol in cystic fibrosis (CF) respiratory mucus is partly responsible for its marked adhesiveness and stickiness, which impair mucus transport, and that distearoyl phosphatidylglycerol (DSPG) was the most efficient form of phosphatidylglycerol in the enhancement of respiratory mucus clearance. The aim of our study was to analyse ...

Background: The principal objective of this study was to correlate biophysical properties vaginal discharge present in the cervical mucus with timing fertile window. In particular, we produce measures viscoelasticity secretion using two methods. first uses only elasticity extracted from Creighton Model Fertility Care System (CrMs) scale, calculated P-6 ovulation estimated day (OED) respect peak...

We characterize the scale-dependent rheological properties of mucus from the Chaetopterus sea annelid and determine the intrinsic lengthscales controlling distinct rheological and structural regimes. The mucus produced by this ubiquitous filter feeder serves a host of roles including filtration, protection and trapping nutrients. The ease of clean mucus extraction coupled with similarities to h...

  Background and Objective: Chronic rhinosinusitis (CRS) is one of the most common chronic diseases. In the past decades, there has been an increase in fungal infections of sinuses and fungal rhinosinusitis (FRS) has been diagnosed more frequently. Knowing the fungal flora and its prevalence in CRS patients will allow a better understanding of this disease, permitting a correct diagnosis, trea...

Increased mucus production is a common cause of morbidity and mortality in inflammatory airway diseases, including asthma, chronic obstructive pulmonary disease (COPD), and cystic fibrosis. However, the precise molecular mechanisms for pathogenic mucus production are largely undetermined. Accordingly, there are no specific and effective anti-mucus therapeutics. Here, we define a signaling pathw...

The colonic mucus layer serves as an important barrier and prevents colonic bacteria from invading the mucosa and cause inflammation. The regulation of colonic mucus secretion is poorly understood. The aim of this study was to investigate the role of the mucus barrier in induction of colitis. Furthermore, regulation of mucus secretion by luminal bacterial products was studied. The colon of anes...

The external mucus layers of the stony coral Porites astreoides and the soft corals Palythoa sp. and Heteroxeniu fuscesens are inhabited by communities of marinc heterotrophic bacteria. Population levels of bacteria in coral mucus may be regulated by the self-cleaning behavior of the host. Bacterial populations in coral mucus respond to stresses applied to the host coral by growing to higher po...

We describe a method that permits the collection of very small samples (2 nl) from precisely defined positions within the gastric mucus of anesthetized mice. This method was used to study the in vivo local distribution of bacteria within the mucus of Helicobacter felis-infected mice. A total of 200 samples from 40 mice were analyzed. Each sample was microscopically analyzed, within less than 1 ...

BACKGROUND Retention of airway secretions is a common and serious problem in ventilated patients. Treating or avoiding secretion retention with mucus thinning, patient-positioning, airway suctioning, or chest or airway vibration or percussion may provide short-term benefit. METHODS In a series of laboratory experiments with a test-lung system we examined the role of ventilator settings and lu...