Net endogenous acid production (NEAP) can be estimated by a primarily anthropometry-dependent organic acid anion (OA) component and the particularly diet-dependent potential renal acid load (PRAL). However, there is evidence that certain foods may also impact on the OA component. Here, we discuss measurements of urinary 24-h OA excretion obtained in healthy subjects, against the background of r...

1. The fate of (-)-quinic acid has been investigated in 22 species of animals including man. 2. In man and three species of Old World monkeys, i.e. rhesus monkey, baboon and green monkey, oral quinic acid was extensively aromatized (20-60%) and excreted in the urine as hippuric acid, which was determined fluorimetrically. 3. In three species of New World monkeys, i.e. squirrel monkey, spider mo...

In 1963 Umberger and Fiorese (1) introduced a colorimetric method for HA,1 based on the color reaction of HA, dissolved in anhydrous pyridine, with BSC. Therefore, for applying their method to determine HA in urine, HA must first be extracted from the urine. We found that HA dissolved in water-pyridine (1:1, by vol) produces a red-orange color when BSC is added at room temperature. The absorpti...

BACKGROUND We assessed the bioavailability of orange juice (poly)phenols by monitoring urinary flavanone metabolites and ring fission catabolites produced by the action of the colonic microbiota. OBJECTIVE Our objective was to identify and quantify metabolites and catabolites excreted in urine 0-24 h after the acute ingestion of a (poly)phenol-rich orange juice by 12 volunteers. DESIGN Twel...

The problem of the origin of the glycine available for hippuric acid synthesis after the administration of benzoic acid or its salts has been studied by many investigators with varying results. It should be borne in mind, in this connection, that all species of animals do not react similarly in response to the ingestion of benzoic acid. Thus the organisms of man (l), the rabbit (2), the goat (3...

Epidemiological studies have suggested an inverse correlation between red wine consumption and the incidence of CVD. However, Champagne wine has not been fully investigated for its cardioprotective potential. In order to assess whether acute and moderate Champagne wine consumption is capable of modulating vascular function, we performed a randomised, placebo-controlled, cross-over intervention ...