نتایج جستجو برای: toxicity studies

تعداد نتایج: 1520932  

2014
Rimi Miyaoka Masahito Hosokawa Masahiro Ando Tetsushi Mori Hiro-o Hamaguchi Haruko Takeyama

The study of spatial distribution of secondary metabolites within microbial cells facilitates the screening of candidate strains from marine environments for functional metabolites and allows for the subsequent assessment of the production of metabolites, such as antibiotics. This paper demonstrates the first application of Raman microspectroscopy for in situ detection of the antifungal antibio...

Journal: :Environmental Health Perspectives 2000
J To-Figueras C Barrot M Sala R Otero M Silva M D Ozalla C Herrero J Corbella J Grimalt J Sunyer

A set of 53 individuals from a population highly exposed to airborne hexachlorobenzene (HCB) were selected to study the elimination kinetics of this chemical in humans. The volunteers provided blood, 24-hr urine, and feces samples for analysis of HCB and metabolites. The serum HCB concentrations ranged from 2.4 to 1,485 ng/mL (mean +/- SD, 124 +/- 278), confirming that this human population has...

Journal: :Journal of pain and symptom management 2004
Mervyn Dean

This article reviews the literature pertaining to the metabolism of several of the commonly used opioids, and the known activity of their metabolites. The effect of renal failure on the pharmacokinetics of these drugs and metabolites is then reviewed. Finally, the effect of renal dialysis on opioid drugs and metabolites is reviewed. Based on the review, it is recommended that morphine and codei...

Journal: :Journal of Experimental Medicine 1946

Journal: :Journal of Pharmacology and Toxicology 2007

Journal: :Environmental Health Perspectives 1989

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