The distribution of fibrinolytic activity in tissues may be studied by the technique of fibrinolysis autography (Todd, 1958, 1959, 1960). This is a histological method in which a section of fresh tissue is incubated in contact with a thin layer of bovine fibrin. During incubation discrete zones of digestion appear in the fibrin, related presumably to concentrations of fibrinolytic enzymes in th...

In the case of some infinite domains, it is shown that the spectrum of the elasticity theory operator is not purely continuous. This implies the existence of a new class of the so-called topographical waveguides. §

UNLABELLED Topographical disorientation (TD) has not been as extensively studied as other frequent manifestations of Alzheimer's disease (AD). OBJECTIVE To verify the occurrence of TD and to identify the neuropsychological dysfunctions associated with TD in AD. METHOD Thirty patients with probable AD, their caregivers and 30 subjects without dementia (controls) were interviewed with a quest...

Studies of patients with focal brain damage suggest that topographical representation is subserved by dissociable neural subcomponents. This article offers a condensed review of the literature of "topographical disorientation" and describes several functional MRI studies designed to test hypotheses generated by that review. Three hypotheses are considered: (i) The parahippocampal cortex is crit...

BACKGROUND AND PURPOSE Microbleeds (MBs) visualized by use of T2*-weighted gradient-echo MR imaging are pathologic blood-breakdown products after tiny cerebral hemorrhages. The topographic distribution of the lesions has not been compared with that of symptomatic intracerebral hemorrhage (ICH). The purpose of this study was to evaluate the distribution of MBs in the pontocerebellar region and t...

The experience of numerous cases of surgical operations carried out over the ten years from 1990-2000, has meant we have been able to reflect on the fact that the median, ulnar, radial (upper extremity), tibial and external popliteal sciatic (lower extremity) nerves are more greatly exposed to compressive pathology. This is due to certain anatomical topographical relationships with canals, semi...