Objective: The purpose of the current study was to investigate the in vivo (analgesic, antidiarrheal, neurological, and cytotoxic) and in vitro (antioxidant, antimicrobial, thrombolytic and anthelmintic) activity of different fractions of methanolic extract of Momordica charantia. Materials and Methods: The antioxidant property ...

BACKGROUND AND PURPOSE Arterial recanalization and subsequent reperfusion have extensively demonstrated their ability to restore the brain function when performed shortly after acute ischemic stroke. However, arterial recanalization does not necessarily lead to brain tissue reperfusion. SUMMARY OF REPORT This review provides an update of current approaches to improve the efficacy profile of b...

Time-dependent thrombolytic resistance is a critical problem in thrombolytic therapy for acute myocardial infarction. Platelets have been regarded as the main source of plasminogen activator inhibitor-1 (PAI-1) found in occlusive plateletrich clots. However, endothelial cells are also known to influence the fibrinolytic capacity of blood vessels, but their ability to actively mediate time-depen...

Thrombolytic therapy is not recommended for acute ischemic stroke (AIS) in patients under the age of 18 and published experience is limited. In this case report, we describe two children treated with systemic thrombolytic therapy. One child received additional mechanical revascularization and achieved a good clinical outcome. The differences in the fibrinolytic system and the different etiology...

A patient's refusal to receive blood products can pose both clinical and ethical challenges to the surgeon. In this report, we review the case of a Jehovah's Witness presenting with critical lower limb ischemia and severe anemia for whom the decision of whether to perform thrombolytic therapy was complicated by his refusal to accept blood products. The case demonstrates that thrombolytic therap...

OBJECTIVES We sought to assess the efficacy and safety of thrombolytic therapy in patients with an acute pulmonary embolism (PE). BACKGROUND Thrombolytic therapy is approved for the treatment of acute PE; however, the safety and efficacy of this therapy remain debated. METHODS A meta-analysis of randomized, controlled trials comparing thrombolytic agents with intravenous heparin in patients...

background: humans have been involved with the phenomena of pain and pain relief from the ancient times. back pain is the most common pain. in fact, eight out of ten people experience it in their lifetime. however, individuals with specific jobs, including nurses, are faced with this problem more. nursing is in the top ten careers suffering from the most severe musculoskeletal injuries. there a...

background: to determine the prevalence and patterns of complementary and alternative medicine (cam) use in urban population in isfahan. methods: in a cross–sectional study through two-stage sampling methods, 870 individuals were selected from isfahan province, center of iran. we selected 20 clusters randomly and chose one household from each cluster by chance then 24 households were included...

removal of smear layer and disinfection of canals are important objectives of teeth root canal cleaning. in order to achieve this purpose, rinsing substances, intra canal drugs as well as ultrasound are used. today, use of laser to remove smear layer and to disinfect root canals has increasingly attracted the attentions. till now different lasers such as co2, nd:yag, er:yag, er,cr:ysgg have bee...

this study sought to determine the level of adherence to coartem© in the routine treatment of uncomplicated malaria among children under the age of five years in nyando district, kenya.seventy-three children below the age of five years with microscopically confirmed uncomplicated plasmodium falciparum malaria and prescribed coartem(®) during the normal outpatient department hours were included ...