PURPOSE To evaluate tear film stability and optical aberrations in eyes wearing plano Lotrafilcon B contact lenses (CL). METHODS Tear Deformation Time (TDT) and aberrometric parameters were assessed in 86 normal emmetropic eyes before and 6 h after wearing CL. RESULT A statistically significant decrease in TDT and increase in root mean square (RMS) values of higher order aberrations (HOA) w...

We found that the original osmolality of the tear film is regained rapidly subsequent to the installation of hypotonic artificial tears or other nonisotonic solutions. The minor irritation due to nonisotonicity and the increased tear volume both contribute to the increased turnover rate which in turn results in the short half-life (measured in seconds) of these solutions in the eye. Despite the...

I am concerned about the lack of proper scrutiny during the peer review process. Although I exemplify it in one paper in a field in which I have some expertise, I believe that this single case shows severe failure of peer review, and it should not have happened. I refer to the article by Nankivil et al. in the latest edition of IOVS Vol 55 No. 7. There seems to be no evidence of scientific rigo...

Background: The therapeu c administra on of I for thyroid remnant abla on and for metastases comes up with some adverse effects. This study was conducted to inves gate whether single high dose radioiodine therapy affects lacrimal gland func ons or not. Materials and Methods: Seventy‐eight eyes of 39 pa ents, who were diagnosed as differen ated thyroid carcinoma, were objec vely tested with Schi...

Dry eye syndrome is a relatively common disease of the tears and ocular surfaces that results in discomfort, visual disturbance, and tear film instability with possible damage to the ocular surfaces. Microvascular submandibular gland (SMG) transfer offers a surgical alternative for a permanent autologous substitution of tears using the basal secretion of a transplanted SMG. Long-term follow-up ...

Squalene (SQ) possesses a wide range of pharmacological activities (antioxidant, drug carrier, detoxifier, hydrating, emollient) that can be of benefit to the ocular surface. It can come in contact with human meibum (hMGS; the most abundant component of the tear film lipid layer) as an endogenous tear lipid or from exogenous sources as eyelid sebum or pharmaceuticals. The aims of this study wer...

BACKGROUND Recent studies have demonstrated that pterygium has a close relationship with dry eye disease. This study is to determine abnormalities in meibomian gland and tear function in patients with pterygium and to assess the relationship between the variables. MATERIALS AND METHODS Forty eyes from forty patients with primary nasal pterygium and forty eyes from forty volunteers without ocu...

OBJECTIVE To document the clinical and morphologic corneal findings in the early stages of congenital aniridic keratopathy in Swedish families. DESIGN Prospective, observational, comparative case series. PARTICIPANTS A total of 16 eyes of 16 subjects with congenital aniridic keratopathy and a clear central cornea, and 6 eyes from 6 healthy controls (unaffected relatives). Nine of the 16 eye...