نتایج جستجو برای: subcutaneous human adipocyte

تعداد نتایج: 1676266  

Journal: :Circulation 2005
G Rega C Kaun T W Weiss S Demyanets G Zorn S P Kastl S Steiner D Seidinger C W Kopp M Frey R Roehle G Maurer K Huber J Wojta

BACKGROUND Adipose tissue is a prominent source of plasminogen activator inhibitor-1 (PAI-1), the primary physiological inhibitor of plasminogen activation. Increased PAI-1 expression acts as a cardiovascular risk factor, and plasma levels of PAI-1 strongly correlate with body mass index (BMI). Elevated serum levels of interleukin-6 (IL-6), an inflammatory cytokine and a member of the glycoprot...

Journal: :Indian Journal of Dermatology, Venereology, and Leprology 2015

Journal: :Obesity facts 2009
Jürgen Janke Stefan Engeli Kerstin Gorzelniak Friedrich C Luft Jens Jordan

BACKGROUND A widely applied technique to reduce subcutaneous fat pad size involves subcutaneous injection of a phosphatidylcholine preparation ('injection lipolysis'). As the mode of action is mostly unknown, we planned to study cellular effects of the particular drug used in Germany (Lipostabil(R)). METHODS Human preadipocytes, adipocytes, vascular and skeletal muscle cells as well as renal ...

2004
Christine Esau Xiaolin Kang Eigen Peralta Elaine Hanson Eric G. Marcusson Lingamanaidu V. Ravichandran Yingqing Sun Seongjoon Koo Ranjan J. Perera Ravi Jain Nicholas M. Dean Susan M. Freier C. Frank Bennett Bridget Lollo Richard Griffey

MicroRNAs (miRNAs) are endogenously expressed 20–24 nucleotide RNAs thought to repress protein translation through binding to a target mRNA (1–3). Only a few of the more than 250 predicted human miRNAs have been assigned any biological function. In an effort to uncover miRNAs important during adipocyte differentiation, antisense oligonucleotides (ASOs) targeting 86 human miRNAs were transfected...

Journal: :Journal of animal science 2003
P Eguinoa S Brocklehurst A Arana J A Mendizabal R G Vernon A Purroy

The effects of sex, genotype, and adipose depot on lipogenic enzyme activity have been investigated in Holstein and Pirenaican bulls and heifers, taking into account differences in adipocyte size. Fifteen Pirenaican bulls and 15 heifers and 15 Holstein bulls and 13 heifers were fattened until slaughter (12 to 13 mo old and 450 to 500 kg of body weight). During the fattening period, animals had ...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2008
Odile Poulain-Godefroy Cécile Lecoeur François Pattou Gema Frühbeck Philippe Froguel

Obesity is characterized by systemic low-grade inflammation in which adipose tissue, especially the omental depot, is thought to play a key role. We have previously shown that inflammation impairs 3T3-L1 preadipocyte cell line differentiation. To explore whether this interaction also takes place in vivo, the expression of several genes related to inflammation and adipocyte differentiation was a...

Journal: :International journal of molecular medicine 2011
Per-Arne Svensson Margareta Jernås Kajsa Sjöholm Jenny M Hoffmann Bengt E Nilsson Magnus Hansson Lena M S Carlsson

Brown adipose tissue (BAT) has profound effects on body weight and metabolism in rodents. Recent reports show that human adults have significant amounts of BAT. Our aim was to study the gene expression profile of human BAT. Biopsies of adipose tissue with brown-red color and subcutaneous white adipose tissue (WAT) were obtained from 24 patients undergoing surgery in the thyroid region. Intrasca...

2016
Olaia Urrutia José Antonio Mendizabal Kizkitza Insausti Beatriz Soret Antonio Purroy Ana Arana

This study examined the effect of linseed and algae on growth and carcass parameters, adipocyte cellularity, fatty acid profile and meat quality and gene expression in subcutaneous and intramuscular adipose tissues (AT) in lambs. After weaning, 33 lambs were fed three diets up to 26.7 ± 0.3 kg: Control diet (barley and soybean); L diet (barley, soybean and 10% linseed) and L-A diet (barley, soy...

Journal: :The British journal of nutrition 2008
Anabelle Redonnet Carine Ferrand Céline Bairras Paul Higueret Catherine Noël-Suberville Pierrette Cassand Claude Atgié

In order to study the effects of dietary lipids and vitamin A on the development of adipose tissues, young rats were submitted for 8 d to a control or to two cafeteria diets with normal (Caf) or higher (Caf + ) vitamin A levels. Retinoid (retinoic acid receptor (RAR) a, RARg, retinoid X receptor(RXR) alpha) and fatty acid (PPARgamma) receptor mRNA was measured in the subcutaneous white adipose ...

2013
Umberto Laforenza Manuela F. Scaffino Giulia Gastaldi

BACKGROUND Glycerol outflow from adipocytes has been considered for a decade to be mediated by aquaporin-7, an aquaglyceroporin highly expressed in the adipose tissue. Its involvement in glycerol metabolism has been widely studied also in humans. Recent studies in different aquaporin-7 KO mice models pose two different questions 1) the exact localization of aquaporin-7 in human white adipose ti...

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