Introduction: In the present study, AS1411 aptamer conjugated gold nanoclusters (GNCs) have been introduced as a targeted radiosensitizer for enhancing megavoltage radiation therapy efficacy. RT has identified as an effective therapeutic modality for many different types of solid tumors. However, equal radiation beams absorption by tumor and surrounding healthy tissues is still...

PURPOSE The aim of this study was to investigate the peripheral doses resulting from volumetric modulated arc therapy (VMAT) and intensity modulated radiotherapy (IMRT) techniques in cervical cancer radiotherapy. METHODS Nine patients with cervical cancer had treatment planned with both VMAT and IMRT. A specially designed phantom was used for this study, with ion chambers placed at interest p...

background: attenuation coefficient (μ) plays an important role in calculations of treatment planning systems, as well as determination of dose distributions in external beam therapy, dosimetry, protection, phantom materials and industry. so, its exact measurement or calculation is very important. the aim of this study was to evaluate the μ in different points in the water phantom analytically ...

introduction radiotherapy with small fields is used widely in newly developed techniques. additionally, dose calculation accuracy of treatment planning systems in small fields plays a crucial role in treatment outcome. in the present study, dose calculation accuracy of two commercial treatment planning systems was evaluated against monte carlo method. materials and methods siemens once or linea...

Background: Monoclonal antibodies have confirmed their merit as biotherapeutics across a wide spectrum of diseases, including cancer, heart disease, infection, and immune disorders. Materials and Methods: The dynamics of 89Zr-labelled monoclonal antibodies (MAb) after injection into the human body are modelled. This modified biokinetic model can be used for dose assessment not only for 89Zr-lab...

Introduction: Radiotherapy is a common treatment modality for patients with head and neck malignancies. As the nose lies within the field of radiotherapy of the head and neck, the olfactory fibers and olfactory receptors may be affected by radiation. The aim of this study was to evaluate changes in olfactory threshold in patients with head and neck malignancies who have received radiation to th...

BACKGROUND AND AIMS Growth of bedding plants, in small peat plugs, relies on nutrients in the irrigation solution. The object of the study was to find a way of modifying the nutrient supply so that good-quality seedlings can be grown rapidly and yet have the high root : shoot ratios essential for efficient transplanting. METHODS A new procedure was devised in which the concentrations of nutri...

Extra renal extra cranial malignant rhobdoid tumors (MRT) are rare, frequently lethal and affect mostly children. No definite treatment has been made and the role of radiation therapy is poorly defined. This report explains a 14 year old girl with MRT in her neck soft tissue. She is alive with no evidence of disease 18 months after diagnosis. Through the experience with this case, we suggested...