Parkinson’s disease (PD) is the second most frequent neurodegenerative disorder worldwide. The depletion of dopamine in the nigro-striatal pathway is a main pathological hallmark that requires continuous and focal restoration. Since dopamine does not cross the digestive mucosa or the blood brain barrier, its lipophilic precursor L-dopa has been employed and remains the pivotal oral medication. ...

Sulfur dioxide and other so-called sulfiting agents as additives in foods and drugs may cause severe allergic reactions in susceptible individuals, especially asthmatics. The most widely used chemical preservatives, they have become a subject of increasing concern since 1976. The issue was recently brought to national attention by a CBS "60 Minutes" report on sulfite sensitivity aired twice in ...

Abstract Background Faba bean attacked by soil-borne pathogens causing root rot disease. This disease has serious damage to both plant stand and produced yield. The present study aimed evaluate effectiveness of the bioagents; Trichoderma harzianum some resistance inducers as fungicide alternatives against incidence at pre- post-emergence growth stages. Results Under open greenhouse conditions ,...

Conyza bonariensis (L.) Cronquist is a widespread noxious weed with high fecundity, associated no-till systems such as vineyards and other perennial crops in Mediterranean climates. Seeds germinate staggered flushes, which leads to great variation the growth stage between individuals same field, chemical control becomes challenging. Besides, species have evolved resistance herbicides worldwide,...

OBJECTIVE Near-infrared spectroscopy (NIRS) measurements of tissue oxygen saturation (StO2) are useful for the assessment of skeletal muscle perfusion and function during exercise, however, they are influenced by overlying skin and adipose tissue. This study explored the extent and nature of the influence of adipose tissue thickness (ATT) on StO2. APPROACH NIR spatially resolved spectroscopy ...

BACKGROUND Preservatives present in cosmetics and other industrial products can cause allergic contact dermatitis. The aim of the study was to assess the frequency of allergy to selected preservatives in consecutive patients examined due to contact dermatitis in the Nofer Institute of Occupational Medicine, Łódź, and to establish whether individuals sensitized to formaldehyde react simultaneous...