Background: Diet is considered as an important contributor to the development of the cancers. In the present study, the association of dietary patterns with gastric cancer risk was studied. Methods: In the present case-control study, 192 newly diagnosed gastric cancer patients and 365 subjects as control group were included. The participants in each group underwent face-to-face interview. For ...

the epigenetic alterations like histone modifications , dna methylation and others remarkable categories  including nucleosome remodeling and rna mediated targeting have been strongly investigated  recently .in this way , beside the notable importance of dna methylation ,the histone modifications are the most important issues in the  tumorogenesis and cancer progression. moreover, the fluctuati...

gastric cancer has been known as a poor prognosis disease with a high degree of mortality. in iran, it has been increased during the previous two decades, especially in northern part of the country. the aim of this study was to determine the demographic and clinical characteristics of gastric cancer in mazandaran province. all patients with gastric cancer diagnosis treated in the imam khomeini ...

we examined the effect of potential interfering factors that play major roles in the outcome of our patients with stomach cancer. 100 consecutive patients diagnosed with gastric cancers were prospectively observed, treated and followed from november 2009 to january. absence of helicobacter pylori infection (p=0.027), absence of vascularisation (p<0.001), and undetermined histopathological type ...

background: today the use of laparoscopy before laparotomy is an effective method for decision-making in patients with gastric adenocarcinoma. the reliance on ct scans for decision-making purposes is not only unhelpful, yet also misleading . nonetheless, indications for laparoscopy and its application are changing daily. the low quality of diagnostic tools and epidemiological situation in our c...

A more detailed understanding of the somatic genetic events that drive gastrointestinal adenocarcinomas is necessary to improve diagnosis and therapy. Using data fromhigh-density genomic profiling arrays, we conducted an analysis of somatic copy-number aberrations in 486 gastrointestinal adenocarcinomas including 296 esophageal and gastric cancers. Focal amplifications were substantially more p...

BACKGROUND Detection of tumor-associated genetic alterations in plasma of cancer patients has recently been suggested to be an accurate method for detecting early or recurrent cancer. METHODS We performed quantitative real-time PCR for MYC and GAPDH in tissue and plasma samples of 57 patients with gastric cancer and in plasma of 79 cancer-free individuals. We also performed two-color MYC fluo...

Inflammatory condition is the consequence of defensive mechanism of immune system against viral and bacterial infection, tissue injury, UV radiation, stress and etc. Persistently acute inflammation leads to chronic phase which is characterized by production of pro-inflammatory mediators from T cells. These molecules (e.g. IL-6, TNF-&alpha, IL-1&beta and IL-17) are mostly pleiotropic cytokines i...

background: among all cancers, malignancies of gastrointestinal tract are the most common cancer among iranian population. dietary behavior is thought to be the most important risk factor in gastric cancer. fear and perceived severity are two important constructs of the protection motivation theory (pmt). despite the evidence of the impact of these two constructs in modifying dietary habits aga...