a 36-year-old woman with right upper quadrant abdominal pain since three months previously and no other significant medical history was referred for evaluation of an abdominal mass. upon clinical examination, a large palpable mass in the mid -upper abdominal area was noted. abdominal ultrasound and spiral ct-scan showed a large hepatic mass in the left liver lobe. the patient was referred for t...

Malta Medical Journal Volume 20 Issue 1 March 2008 Introduction The concept of carrying a cytotoxic radionuclide directly to cancerous cells is an attractive alternative to conventional forms of radiation treatment. The very close contact between the radionuclide and the cell to be destroyed enables the absorbed radiation to be concentrated at the site of abnormality with the minimal injury to ...

introduction natural and artificial radionuclides are the main sources of human radiation exposure, which enter the food chain from the environment. radionuclides can affect human health by transferring from soil to plants and entering the human body. in this research study, we aimed to determine the activity concentrations of radionuclides and calculate the average annual committed effective d...

In internal radionuclide therapy, a growing interest in voxel-level estimates of tissue-absorbed dose has been driven by the desire to report radiobiologic quantities that account for the biologic consequences of both spatial and temporal nonuniformities in these dose estimates. This report presents an overview of 3-dimensional SPECT methods and requirements for internal dosimetry at both regio...

To assess ventricular function in patients who have undergone cardiac transplantation, 247 radionuclide ventriculograms were performed on 94 patients. During the first three days after transplantation, 19% demonstrated left ventricular dysfunction and 41% showed isolated right ventricular dysfunction. In 95 cases, radionuclide ventriculography was performed within 24 hr of myocardial biopsy. A ...

PURPOSE To compare CT and radionuclide imaging of osmotic blood-brain barrier disruption. To develop a quantitative method for imaging osmotic blood-brain barrier disruption and to see if iopamidol could be safely given intravenously in conjunction with blood-brain barrier disruption. METHODS Forty-five blood-brain barrier disruption procedures were imaged with CT and radionuclide scans. The ...

The charts of 750 patients were reviewed to determine the value of routinely removing cerebrospinal fluid at the time of myelography and cisternography for chemical and cytologic examination. In most patients cerebrospinal fluid findings were normal. In the few abnormal studies, the findings were often uninformative, superfluous, or insufficient for appropriate diagnosis. In no instance did rou...

OBJECTIVE Adenosine, which has been used for a myocardial perfusion scan, shows rapid clearance from blood because of its short half-life of <10 seconds. This simulation study evaluates influences of modes of radionuclide injection on ventricular adenosine concentration when one intravenous injection line is used. METHODS Assuming that radionuclide injection is a unit impulse, time-activity c...

OBJECTIVE This continuing education article reviews radionuclide bone therapy agents that are available commercially and introduces agents that are being evaluated for future use. Currently these agents are used to provide pain palliation from metastases to bone. Future applications may include adjuvant therapy to surgery or external beam treatment. After reading this paper, the reader should b...