نتایج جستجو برای: qt prolongation
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BACKGROUND Numerous structurally unrelated drugs, including antipsychotics, can prolong QT interval and trigger the acquired long QT syndrome (aLQTS). All of them are thought to act at the level of KCNH2, a subunit of the potassium channel. Although the QT-prolonging drugs are proscribed in the subjects with aLQTS, the individual response to diverse QT-prolonging drugs may vary substantially. ...
BackgroundDose dependent QT prolongation with class III antiarrhythmic initiation mandates close monitoring, often in an inpatient setting. In a majority of patients sotalol loading is uncomplicated and requires no dose adjustment. Dose adjustments when required are most secondary to bradycardia or prolongation. We describe successful outpatient pathway completed using the Kardia 6L ECG pharmac...
background: prolonged qt interval may lead to serious arrhythmias and ventricular fibrillation, hence prevention of the qt-interval prolongation is crucial for physicians. the aim of this study was to assess the influence of intravenous lidocaine on the qtc interval resulting from spinal anesthesia with bupivacaine. methods: in a randomized double blind trial, fifty male patients with mean age ...
AIMS To evaluate changes in QT duration during low-dose haloperidol use, and determine associations between clinical variables and potentially dangerous QT prolongation. METHODS In a retrospective cohort study in a tertiary university teaching hospital in The Netherlands, all 1788 patients receiving haloperidol between 2005 and 2007 were studied; ninety-seven were suitable for final analysis....
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