نتایج جستجو برای: protective antigen

تعداد نتایج: 307620  

Journal: :Infection and immunity 2008
Christine A Shaw Michael N Starnbach

The lethal toxin produced by Bacillus anthracis is a bipartite toxin in which the first protein, protective antigen (PA), transports the second protein, lethal factor, across the host cell membrane. We have previously shown that CD8(+) T-cell epitopes fused to a nontoxic derivative of lethal factor (LFn) are delivered into the host cell cytosol in a PA-dependent manner. Delivery of these antige...

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