ABSTRACT Background: Induction of labour (IOL) or cervical ripening an unfavourable cervix can be achieved by both pharmacological and surgical methods. When the is unripe, Foley catheters prostaglandins method IOL used. In this study, we aimed to compare success rate cost-effectiveness vaginal prostaglandin E2 pessary with catheter. Methods: This quasi-experimental study was conducted at Gynae...

Introduction: The Cannabinoid receptors (CBR) densities are high within the cerebellum. Cannabinoid receptors manipulations have been reported to cause altering the cerebellar functions. harmaline have immune-modulatory effects in several studies. i.e., significant anti-inflammatory effect via the inhibition of prostaglandin E2 (PGE2) and tumor necrosis factor alpha (TNF-α). Endocannabino...

1. Lung resistance was measured by the interruptor method in fifteen patients during infusion of prostaglandin E2 or FZa, for termination of pregnancy. 2. Small but significant reversible elevation in lung resistance occurred in patients receiving both prostaglandins; this was an unexpected finding in the case of prostaglandin E2. 3. The changes described were not harmful in normal subjects, bu...

Prostaglandin E2 (PGE2) blocks mast-cell (MC)-dependent allergic responses in humans but activates MCs in vitro. We assessed the functions of the EP receptors for PGE2 on cultured human MCs (hMCs). hMCs expressed the EP3, EP2, and EP4 receptors. PGE2 stimulated the accumulation of cyclic adenosine monophosphate (cAMP), and suppressed both Fc epsilonRI-mediated eicosanoid production and tumor ne...

1. Prostaglandin E2 induces immediate migraine-like attack in migraine patients without aura. Cephalalgia. 2012 Aug; 32(11):822-33. Epub 2012 Jun 19. 2. The pharmacological effect of BGC20-1531, a novel prostanoid EP4 receptor antagonist, in the prostaglandin E2 human model of headache. J Headache Pain. 2011 Oct; 12(5):551-9. 3. Pro-inflammatory and vasoconstricting prostanoid PGF2 alpha causes...

A B S T R A C T Tlhe precise role of the kidney in spontaneous experimental hypertension is unknown. We have analyzed the rates of renal prostaglandin synthesis by utilizing a spontaneously hypertensive rat model. The synthetic rate of prostaglandin E2, prostaglandin F2a, and prostaglandin A2-like products was measured in vitro with renal microsomes. In the rabbit and rat there is a steep gradi...