The high-order interference (HOI)-The interferogram introduced by polarization mode couplings (PMC) of multiple perturbations-Will cause misjudgment of the realistic coupling points in polarization-maintaining fiber (PMF) which is tested with a white light interferometer (WLI) with large dynamic range. We present an optical path tracking (OPT) method for simplifying the analysis of HOI, and dem...

A reflection fiber inclinometer is proposed and experimentally demonstrated based on two linearly polarized (LP) modes coupling. The configuration consists of a section of polarization-maintaining fiber (PMF) containing a fiber Bragg grating (FBG) splicing with single mode fiber (SMF). Bending the PMF in the upstream of FBG can induce an additional birefringence of PMF, which results in the int...

Myeloproliferative neoplasms (MPNs) are traditionally separated into BCR-ABL-positive chronic myeloid leukemia (CML), and BCR-ABL-negative MPNs including primary myelofibrosis (PMF), essential thrombocythemia (ET), and so forth. One of the diagnostic requirements for PMF and ET is the absence of the Philadelphia chromosome, while its presence is almost universally indicative of CML. However, a ...

Probabilistic matrix factorization (PMF) is a powerful method for modeling data associated with pairwise relationships, finding use in collaborative filtering, computational biology, and document analysis, among other areas. In many domains, there are additional covariates that can assist in prediction. For example, when modeling movie ratings, we might know when the rating occurred, where the ...

PM10-2.5 mass and trace element concentrations were measured in Winston-Salem, Chicago, and St. Paul at up to 60 sites per city during two different seasons in 2010. Positive Matrix Factorization (PMF) was used to explore the underlying sources of variability. Information on previously reported PM10-2.5 tire and brake wear profiles was used to constrain these features in PMF by prior specificat...

Somatic mutations in the calreticulin (CALR) gene were recently discovered in patients with sporadic essential thrombocythemia (ET) and primary myelofibrosis (PMF) lacking JAK2 and MPL mutations. We studied CALR mutation status in familial cases of myeloproliferative neoplasm. In a cohort of 127 patients, CALR indels were identified in 6 of 55 (11%) subjects with ET and in 6 of 20 (30%) with PM...

Heme-copper oxidases (HCOs) are key enzymes in prokaryotes and eukaryotes for energy production during aerobic respiration. They catalyze the reduction of the terminal electron acceptor, oxygen, and utilize the Gibbs free energy to transport protons across a membrane to generate a proton (ΔpH) and electrochemical gradient termed proton motive force (PMF), which provides the driving force for th...

We present a new approach for automated exploration of free energy landscapes on the basis of the umbrella integration (UI) method. The method to search points in the landscape relies on the normal distributions and gradients of the potential of mean force (PMF) obtained from UI calculations. We applied this approach to the alanine dipeptide in solution and demonstrated that the equilibrium and...

Authors Reply. Accepted. We reworded the sentence into the following: PMF is becoming common for organic source apportionment (Zhang et al., 2005; Lanz et al., 2007) and factor analysis of AMS data using PMF in its diverse implementations (including e.g. ME-2) has extracted biomass burning organic aerosol (BBOA) factors in multiple sites (Aiken et al., 2010; Elsasser et al., 2012; Crippa et al....

Positive matrix factorization (PMF) of highresolution laboratory chamber aerosol mass spectra is applied for the first time, the results of which are consistent with molecular level MOVI-HRToF-CIMS aerosolphase and CIMS gas-phase measurements. Secondary organic aerosol was generated by photooxidation of dodecane under low-NOx conditions in the Caltech environmental chamber. The PMF results exhi...