CASE SUMMARY This report describes a 4-year-old cat with chronic intermittent haematochezia and faecal incontinence of 7 months' duration. Investigation revealed severe colonic multifocal mucosal ulcerations and infiltration of the mucosal lamina propria by large numbers of periodic acid-Schiff-positive macrophages. Fluorescence in situ hybridisation analysis of colonic biopsies revealed multif...

.............................................................................................................................. 2 DECLARATION ....................................................................................................................... 3 ACKNOWLEDGMENTS ......................................................................................................... 4 TABLE OF C...

Whipple's disease commonly presents as chronic diarrhea and abdominal pain. Ascites is an uncommon presentation of Whipple's disease. Here, we report a rare case of a 47-year-old male who presented with diarrhea and abdominal distention for three months. The physical examination was significant for ascites. Serum albumin was low and serum-to-ascites albumin gradient was < 1.1 g/dl. This suggest...

To the best of our knowledge, we present here the first report of a case involving granulomatous pododermatitis caused by Fusarium proliferatum in a 10-year-old female cat. A cutaneous mass developed on the foot-pad of the right hind leg. Nodular granulomatous dermatitis with numerous macrophages and multinucleated giant cells containing cytoplasmic fungal structures were revealed on histologic...

It is true that mycological culture has a higher specificity, but it has lower sensitivity as compared to histopathology with periodic acid-Schiff staining (HP/ PAS).[1,2] HP/PAS is relatively quick, and a specificity of 72% cannot be overlooked.[3] In most cases, morphological aspect of the hyphae and/or spores can suggest the group to which pathogens belong.[3] In personal view of the authors...

We report the first case of hepatoid adenocarcinoma of the skull base, as well as the first reported case in the head and neck region. Hepatoid adenocarcinoma is a rare, aggressive, extrahepatic malignancy with a distinct morphological similarity to hepatocellular carcinoma, in the absence of primary hepatic disease. A 45-year-old man presented with sinus headaches and retro-orbital pain and wa...

Pulmonary alveolar proteinosis is a rare type of interstitial lung disease characterised by diffuse involvement and filling of distal air spaces by the amorphous, periodic-acid-schiff positive lipoproteinaceous material. Whole lung lavage is presently the standard mode of management of such cases. A 33-year-old male presented to our centre with cough and breathlessness on exertion. On evaluatio...

A 30-year-old woman suffered intractable gross hematuria of renal origin, which required nephrectomy after failed conservative management. Pathological examination revealed massive intratubular hemorrhage and frequent deposition of an amorphous and homogenous material positive for Periodic Acid-Schiff (PAS) stain in the corticomedullary junction. This substance is frequently herniated into the ...

Abbreviations: EVG, elastic van Gieson; MRI, magnetic resonance imaging; PAS, periodic acid-Schiff Mammary Paget’s disease is usually localized in the nipple epidermis and lactiferous duct near the nipple (Lloyd et al., 2000). Breast conservative therapy has been attempted for such a patient (Pierce et al., 1997). However, this method may not be appropriate for all patients with Paget’s disease...