Fecal bile acids were analyzed by gas chromatography in IO patients with colon cancer, 25 patients with colon polyp and lO patients with peptic ulcer. On admission total bile acid excretion in patients with colon cancer was significantly higher than in patients with peptic ulcer (P<O.Ol). Also, concentra.tion of cholic acid, chenodeoxychoic acid and primary bilc acids in patients with colon ca...

BACKGROUND Perforated peptic ulcer is a serious complication of peptic ulcers with potential risk of grave complications. There is paucity of published reports on perforated peptic ulcer disease in our local environment. This study was conducted to evaluate the clinical presentation, management and outcome of patients with peptic ulcer perforation in our setting and to identify predictors of ou...

When scientists identified Helicobacter pylori as an infectious agent responsible for peptic ulcer disease, it completely transformed our understanding of the microbiology and pathology of the human stomach. That was in 1982. Before then, “no acid, no ulcer” succinctly described the accepted medical paradigm: stomach ulcers occurred when excess acid damaged the gastric mucosa, and treatment sho...

background peptic ulcer disease is a multifactorial health problem affecting almost all populations worldwide. large scale population-based studies are crucial to understanding its scope and specifications in various nations. we aimed to explore environmental risk factors of peptic ulcer disease in the first population based study in ardabil, northwest iran. methods this study was a part of a l...

objective: it has been noted that the presence of helicobacter pylori (h. pylori) in the oral cavity may affect the outcome of eradication therapy. this condition is associated with the recurrence of gastric infection. the optimum secretion of saliva promotes oral health consequently influencing h. pylori eradication. the purpose of this study was to investigate the relation between salivary se...

background: cd1d presents glycolipid antigens to invariant natural killer t (inkt) cells. the role of cd1d in the development of peptic ulcer and gastric cancer has not been revealed, yet. objective: to clarify the expression of alternatively spliced variants of cd1d in peptic ulcer and gastric cancer. methods: patients with dyspepsia were selected and divided into three groups of non-ulcer dys...