Reprint requests to: Dr. Te-Chang Wu Department of Radiology, Chi-Mei Foundation Hospital. No. 901, Chung Hwa Road, Yong-Kong, Tainan 710, Taiwan, R.O.C. Three children of unilateral type I Duane’s retract ion syndrome (DRS), aged 8 years, 14 months and 2 years were confirmed by demonstration of absence of ipsilateral abducens nerves on 3D fast imaging employing steady-state acquisition (FIESTA...

Recurrent infection of the ocular surface by herpes simplex virus type I (HSV-1), a neurotropic herpesvirus, is a leading infectious cause of corneal blindness in developed countries. The origin of recurrent infections lies in the fact that the virus establishes latency in sensory neurons of the trigeminal ganglion (TG). While the latent infection of TG is marked by the loss of viral protein sy...

PURPOSE To identify the causative mutation with its possible origin in a Chinese family with congenital fibrosis of extraocular muscles type 1 (CFEOM1) and to characterize the ocular phenotypes and lesions in the corresponding intracranial nerves. METHODS Three affected siblings and their asymptomatic parents underwent comprehensive ophthalmic examinations and neuropathologic analysis involvi...

Purpose To report a case of regained corneal sensation and function in a patient with neurotrophic keratopathy due to direct damage to the long ciliary nerves by performing a corneal neurotization procedure using ipsilateral supraorbital nerve. Surgical technique is described in detail as well as a review of the literature on corneal neurotization. Observations A patient with devastating corn...

PURPOSE To determine the involvement of noradrenergic and other vasoconstrictor nerves in the contraction of ocular arteries and the modification by cholinergic and nitroxidergic nerves of vasoconstrictor nerve function. METHODS Changes in isometric tension were recorded in helical strips of the canine posterior ciliary and external ophthalmic arteries denuded of the endothelium, which were s...

PURPOSE To improve understanding of vision loss and clinical findings, we studied gross and microscopic pathology of retinas and optic nerves of individuals with Terson's syndrome. DESIGN Retrospective case series with clinicopathologic correlation. PARTICIPANTS We included 109 deceased individuals with Terson's syndrome. METHODS Histologic sections and gross photographs from 109 cases of...

PURPOSE To analyze the in vivo morphology of corneal cells and nerves in patients with rheumatoid arthritis (RA), with or without secondary Sjögren's syndrome (SSII), and to investigate the correlations between corneal alterations and RA activity. METHODS Fifty patients with RA and 30 age- and gender-matched control subjects were studied. SSII was diagnosed according to the American-European ...

A lthough leprosy is no longer a health problem in developed countries, it continues to affect millions of people in large parts of Asia, Africa, and Latin America. Effective chemotherapeutic treatments are available that have reduced the global disease burden dramatically, but there remain important challenges to fi ghting and controlling the disease. Leprosy is a chronic infection of the skin...

Jonathan Hutchinson (1865-6) was the first person to distinguish herpes zoster ophthalmicus from erysipelas, and he described 18 cases, one of which developed a third nerve palsy. Hutchinson stated that zoster never affected the cheek at all, but a few years later Head and Campbell (1900) described a case with affection of the mandibular branch; Paton (1926) reported a case with involvement of ...

Retinal ischemia is a common pathomechanism in many ocular disorders such as age-related macular degeneration (AMD), diabetic retinopathy, glaucoma or retinal vascular occlusion. Several studies demonstrated that ischemia/reperfusion (I/R) leads to morphological and functional changes of different retinal cell types. However, little is known about the ischemic effects on the optic nerve. The go...