Abstract:Purpose:This study was designed determine the efficacy of bupropion versus placebo in subjects with negative symptoms of schizophrenia.Methods:A convenience sample of 40 patients of both genders aged 18-60 years who were living in psychiatric care centers were randomly treated with bupropion (started with 75 mg twice a day; increased to 100 mg thrice daily) or placebo. The diagnosis of...

Background: The nature of the premenstrual condition is based upon premenstrual symptoms, which women experience them and only in those cases where symptoms have negative influence on the physical, psychological or social functioning; we speak of a premenstrual syndrome, which reduce quality of life. The objective of this study is to assess frequency and severity of PMS in Medical Science Unive...

Over the last 20 years, SPECT and PET, along with CT and MRI have been the main methodologies used in studies investigating psychiatric disorders. The structural alterations in patients’ brains found by CT and MRI are usually quite subtle, while those found by the nuclear imaging modalities (PET and SPECT) are more pronounced. Partly for this reason, the latter methods have led to discoveries i...

Background: Given that on the one side considerable similarities between hypochondriasis and obsessivecompulsive disorder (OCD) by means of sharing a number of features, including intrusive thoughts and repeated checking (Barsky, 1992), on the other side similar structural neuroimaging data that found hypochondriac patients to have significantly smaller mean left and right OFC, and greater left...

Over the last two decades, deep brain stimulation has become widely accepted as a treatment for Parkinson’s disease, dystonia and tremor, and its use is increasing in disorders such as obsessivecompulsive disorder, depression and pain. The primary objective is always to achieve symptom suppression with few or no side effects; in other words, to attain as wide a therapeutic window as possible. I...

Trinucleotide, or triplet, repeats consist of 3 nucleotides consecutively repeated (e.g., CAG CAG CAG CAG) within a region of DNA. All possible combinations of nucleotides are known to exist as triplet repeats, although some are more common than others. These repeated sequences are found both within gene boundaries and in the large stretches of DNA that lie benveen genes. If the triplet repeats...

Introduction: The findings of the quantitative EEG power-spectral studies in obsessive-compulsive disorder (OCD) have so far been mostly inconsistent. Moreover, none of the studies has been a high resolution one. Aim: The aim of the study was to examine the band power of delta, theta, alpha, beta1 and beta2 bands with high resolution EEG data in patients with obsessivecompulsive disorder and co...

for both the orbits. A quick neurologic examination revealed a completely delirious state; initial orbital ultrasonography showed collapsed ocular coats without visible contents/foreign body, subsequent computed tomography of the head and orbit showed no visible globe in either of the orbits with soft tissue edema (Figure 2). There was no evidence of intracranial bleed or major organ damage and...

The aims of this ex post facto study were to determine the comorbidity of personality disorders (PD) with eating disorders (ED), to establish the prominent characteristics of eating disorders subtypes and to compare PDs appeared in patients with EDs with those in other clinical and normal samples. Using the International Personality Disorders Examination (IPDE), 84 outpatients with EDs were com...