BACKGROUND Patch testing is an essential procedure in the investigation of eczema in children. OBJECTIVES To analyse the frequency of contact hypersensitivity and allergic contact dermatitis among Polish children with eczema. PATIENTS/METHODS During an allergy screening programme involving 9320 children aged 7 and 16 years, 12.6% reported symptoms of chronic/recurrent eczema. From this grou...

Background. The frequency of contact allergens is often regionally different and hence it regional identification is important for the prevention of allergic contact dermatitis (ACD). Objectives. The aim of the study was to determine the most common contact allergens in the etiology of ACD from 2008-2012 and evaluate their dynamics in comparison with similar studies in the Czech Republic and in...

Nickel allergy is the most common cause of allergic reactions worldwide, with cutaneous and systemic effects potentially affecting multiple organs. Monocytes are precursors of not only macrophages but also dendritic cells, the most potent activators of nickel hypersensitivity. Monocytes are themselves important antigen-presenting cells, capable of nickel-specific T-cell activation in vivo and i...

BACKGROUND The role of palladium and nickel sensitization in oral disease and dermatitis is not fully understood. OBJECTIVES To investigate whether sensitization to these metals was associated with exposure to dental alloys and oral and skin complaints/symptoms in a European multicentre study. METHODS In six dermatology clinics, patch tests with palladium (3% Na2 PdCl4 ; Pd = 102.0 µmol/g) ...

Although contact dermatitis (CD) from eyeglass frames is uncommon, occasionally it may be encountered. Various substances may cause allergic CD, including metals, cosmetics, plastics, rubber, solvents, antioxidants, dyes, and waxes, some of which can be found in the average eyeglass frame. Recently, it has been determined that plasticizers, UV stabilizers and nickel are the most common allergen...