The structural and magnetic properties of rare-earth nanocomposite magnets of a (Nd,Dy)(Fe,Co,Nb,B)5.5 single layer and a (Nd,Dy)(Fe,Co,Nb,B)5.5/α-Fe multilayer prepared by sputtering and heat treatment have been investigated. Incomplete exchange coupling behaviour is observed in the Ti-buffered NdDyFeCoNbB + 40 wt%Fe single layer magnet. After annealing, the laminated nanostructure consisting ...

The resistance of a Novikoff hepatoma cell line (Ni -Si I FdUrd) to 5-fluorouracil (FUra) was reversed by the inclusion of inosine in the culture medium. As the concentration of inosine in the medium was increased, there was a marked increasein the uptakeof [14C]FUra nd conversionto nucleo tides with a corresponding increase in the incorporation into RNA. While FUra alone had no effect on this ...

BACKGROUND Hemophilia A is a congenital bleeding disorder caused by defective or deficient factor VIII (FVIII). The active form of FVIII is the co-factor for the serine protease factor IXa (FIXa) in the membrane-bound intrinsic tenase (FVIIIa-FIXa) complex. The assembly of the FVIIIa-FIXa complex on the activated platelet surface is critical for successful blood clotting. OBJECTIVES To charac...

AIMS In this study, a loop-mediated isothermal amplification (LAMP) assay has been developed and evaluated for the rapid and sensitive detection of Verticillium dahliae Kleb., the causal agent of vascular wilts in many economically important crops. METHODS AND RESULTS LAMP primers were designed based on a previously described RAPD marker, and the LAMP assay was applied for direct detection of...

A classical velocity centrifugation technique was used to study the in vitro uptake of the new ketolide ABT-773 by human polymorphonuclear neutrophils (PMNs) and a myelomonoblastic cell line, PLB-985, which can be differentiated into PMNs under certain culture conditions, compared to that of HMR 3004. ABT-773 was rapidly taken up by PMNs (cellular concentration to extracellular concentration ra...

Itraconazole (ITZ) is a potent inhibitor of CYP3A in vivo. However, unbound plasma concentrations of ITZ are much lower than its reported in vitro Ki, and no clinically significant interactions would be expected based on a reversible mechanism of inhibition. The purpose of this study was to evaluate the reasons for the in vitro-in vivo discrepancy. The metabolism of ITZ by CYP3A4 was studied. T...

Planar waveguides made of Nd 3+ -doped silicon rich silicon oxide (SRSO) and silicon rich silicon nitride (SRSN) have been fabricated by reactive magnetron sputtering and characterized with special emphasis on the comparison of the guided photoluminescence (PL) properties of these two matrices. Guided fluorescence excited by top surface pumping at 488 nm on planar waveguides was measured as a f...

BACKGROUND AND OBJECTIVE Recently Erbium (Er) YAG laser has been developed for dentistry. It may be suitable for periodontal therapy. This study examined the bactericidal effect of the Er: YAG laser on periodontopathic bacteria in vitro. STUDY DESIGN/MATERIALS AND METHODS After spreading the bacterial suspension of Porphyromonas gingivalis or Actinobacillus actinomycetemcomitans on agar plate...

Since the introduction of Holmiun YAG (Ho-YAG) laser to treat kidney or ureteral stones, a dramatic change in techniques of stone treatment has occurred, especially how to adjust the ideal laser setting to achieve ideal fragmentation. First reports of Ho-YAG laser clinical application had been focused on tissue cutting or destruction (1), but few years later, the ability to fragment stones thro...

OBJECTIVE This study investigates the effects of Nd:YAG laser irradiation combined with different irrigation protocols on the marginal seal of root fillings. BACKGROUND DATA Limited information exists regarding the effects of morphologic changes to root canal (RC) walls after Nd:YAG laser irradiation after smear-layer removal with EDTA on the sealing ability of root fillings. METHODS The 75...