We have developed a snapshot spectral imaging system which fits onto the side camera port of a commercial inverted microscope. The system provides spectra, in real time, from multiple points randomly selected on the microscope image. Light from the selected points in the sample is directed from the side port imaging arm using a digital micromirror device to a spectrometer arm based on a dispers...

We have developed a digital light modulation system that utilizes a modified commercial projector equipped with a laser diode as a light source for quantitative measurements of in vivo tissue oxygenation in an unanesthetized zebrafish embryo via phase-based phosphorescence lifetime detection. The oxygen-sensitive phosphorescent probe (Oxyphor G4) was first inoculated into the bloodstream of 48 ...

Progress in laser technology has led to very compact but nevertheless powerful laser sources. In the visible and near infrared spectral region, lasers of any wavelength can be purchased. Continuous wave laser sources pose an especially serious threat to the human eye and electro-optical sensors due to their high proliferation and easy availability. The manifold of available wavelengths cannot b...

We present a new approach to optical interconnections, based on microelectromechanical system tip/tilt mirror technology and the White cell. This is a free-space approach in which many beams circulate simultaneously in the device, each beam forming a unique spot pattern on the micromirror array. On each bounce, each beam can be switched to any of several White cells, each of which has a differe...

The production of commercial DNA microarrays is based on a light-directed chemical synthesis driven by a set of masks or micromirror arrays. Because of the natural properties of light and the ever shrinking feature sizes, the arrangement of the probes on the chip and the order in which their nucleotides are synthesized play an important role on the quality of the final product. We propose a new...

A thin, agile multiresolution, computational imaging sensor architecture, termed PANOPTES (processing arrays of Nyguist-limited observations to produce a thin electro-optic sensor), which utilizes arrays of microelectromechanical mirrors to adaptively redirect the fields of view of multiple low-resolution subimagers, is described. An information theory-based algorithm adapts the system and rest...

This paper describes a light-addressed electrolytic system used to perform an electrodeposition of enzyme-entrapped chitosan membranes for multiplexed enzyme-based bioassays using a digital micromirror device (DMD). In this system, a patterned light illumination is projected onto a photoconductive substrate serving as a photo-cathode to electrolytically produce hydroxide ions, which leads to an...

We present a compact laser scanning two-photon excitation (TPE) microscope for randomaccess imaging based on a low-cost digital micromirror device (DMD) that scans the laser beam in X, Y and Z axes at the DMD pattern rate, i.e. 4.2 ~32.5 kHz. The optical configuration of the TPE microscope is presented in Figure 1. The X, Y, Z scanning is achieved by programming binary hologram patterns [1] to ...

Physical Sciences Inc. (PSI) is developing a longwave infrared (LWIR) compressive sensing hyperspectral imager (CS HSI) based on a single pixel architecture for standoff vapor phase plume detection. The sensor employs novel use of a high throughput stationary interferometer and a digital micromirror device (DMD) converted for LWIR operation in place of the traditional cooled LWIR focal plane ar...

A new full-field 3-D micro surface profilometer using digital micromirror device (DMD)-based fringe projection strategy and confocal principle is presented in the article. In viewing the fact that conventional laser confocal measurement method not only easily encounters undesired irregular scattering problems, but also lack scanning efficiency due to its single-point type measurement, the newly...