X-ray absorption spectroscopy (XAS) has emerged as one of the premier tools for investigating the structure and dynamic properties of metals in cells and in metal containing biomolecules. Utilizing the high flux and broad energy range of X-rays supplied by synchrotron light sources, one can selectively excite core electronic transitions in each metal. Spectroscopic signals from these electronic...

The role of the residues inside the active cavity of metalloproteins can be investigated by using the metal ion itself as a spectroscopic probe. For example in carbonic anhydrase the cobalt(I1) substituted enzyme has allowed us to understand the role of a free histidine hanging in the cavity in lowering the pK of the coordinated water. Substitution of zinc with cobalt(fi) in superoxide dismutas...

Cadmium(II) complexes with thiolate ligands have received considerable attention because of their intriguing structural features and relevance to metalloproteins. In this study, a new cadmium(II)–rhodium(III) trinuclear complex, [Cd{Rh(apt)3}2]Br2·4H2O (1, apt = 3-aminopropanethiolate), was synthesized by the reaction fac-[Rh(apt)3] cadmium bromide. Compound 1 characterized using elemental anal...