The mathematical model of portfolio optimization is usually represented as a bicriteria optimization problem where a reasonable trade–off between expected rate of return and risk is sought. In a classical Markowitz model the risk is measured by a variance, thus resulting in a quadratic programming model. As an alternative, the MAD model was proposed where risk is measured by (mean) absolute dev...

We employ the recently installed near infrared Multi-Conjugate Adaptive Optics demonstrator (MAD) to determine basic properties of a newly identified, old and distant, Galactic open cluster (FSR 1415). The MAD facility remarkably approaches the diffraction limit, reaching a resolution of 0. 07 (in K), that is also uniform in a field of ∼ 1.8 in diameter. The MAD facility provides photometry tha...

Computerized generation of humor is a notoriously difficult AI problem. We develop an algorithm called Libitum that helps humans generate humor in a Mad Lib R ©, which is a popular fill-in-the-blank game. The algorithm is based on a machine learned classifier that determines whether a potential fill-in word is funny in the context of the Mad Lib story. We use Amazon Mechanical Turk to create gr...

The Logarithmic Number System (LNS) offers good performance for some multimedia applications at low precisions. Motion estimation is a key part of the MPEG encoding system. Usually the motion estimation is performed by using a fixed-point Mean Absolute Difference (MAD) cost function for block matching. LNS Mean Larger Ratio (MLR) is another cost function which can produce comparable video encod...

The square G of a graph G is the graph obtained from G by adding an edge between every pair of vertices having a common neighbor. A proper coloring of G is also called a 2-distance coloring of G. The maximum average degree Mad(G) of a graph G is the maximum among the average degrees of the subgraphs of G, i.e. Mad(G) = max { 2|E(H)| V (H) |H ⊆ G } . Graphs with bounded maximum average degree ar...

Recently security has became one of the major concern in Information System (IS) development. Different security modeling language or security extension is used to model security features of IS. Mal Activity Diagram (MAD) is used at the design stage to represent security aspect. But it cannot model all the security risk management concepts. Without full coverage of concepts, it is not possible ...

BACKGROUND Obstructive sleep apnea syndrome (OSAS) is a major public health problem which affects between 5 to 10% of the general population. OSAS is known to be associated with high rates of morbidity and mortality mainly due to cardiovascular diseases and traffic accidents. The burden of illness is high for the individual and society. There are 2 treatment options for OSAS, Continuous Positiv...

The use of a mandibular advancement device (MAD) increases the activity of the temporo-mandibular (TM) complex and masseter (MM) muscles with the risk of reducing treatment compliance. Predictors of treatment outcome are of importance in selecting patients who might benefit from MAD without side effects. The role of mandibular advancement (MA) during drug-induced sleep endoscopy (DISE) is contr...

MAD-Bayes (MAP-based Asymptotic Derivations) has been recently proposed as a general technique to derive scalable algorithm for Bayesian Nonparametric models. However, the combinatorial nature of objective functions derived from MAD-Bayes results in hard optimization problem, for which current practice employs heuristic algorithms analogous to k-means to find local minimum. In this paper, we co...

Drosophila Nemo is the founding member of the Nemo-like kinase (Nlk) family of serine/threonine protein kinases that are involved in several Wnt signal transduction pathways. Here we report a novel function for Nemo in the inhibition of bone morphogenetic protein (BMP) signaling. Genetic interaction studies demonstrate that nemo can antagonize BMP signaling and can inhibit the expression of BMP...