Fifty years have passed since a visit to the United States set in train the building in Britain of the world’s first business computer. The computer was built by J. Lyons & Co., then Britain’s leading caterer with a household name for its teashops, its packeted tea and its cakes and ice cream. The system was given the name LEO, Lyons Electronic Office, and on it was run the world’s first regula...

In the above article the reference to Hering, E. (1878/1964) should be (1920/1964). Leo M. Hurvich has kindly pointed out to the author that ‘Outlines of a Theory of the Light Sense’ (Cambridge, Harvard University Press, 1964, translated by Leo M. Hurvich and Dorothea Jameson), is based on Ewald Hering’s ‘Grundzuge der Lehre vom Lichtsinn’ (Berlin, Springer, 1920), and not, as has often been as...

Managing structure: EIBIR/EuroAIM Principal Investigator: Francesco Sardanelli, University of Milan, EuroAIM Director Data manager at the Central Unit in Milan: Rubina M. Trimboli Statistical Analysis at the Central Unit in Milan: Giovanni Di Leo Scientific Advisor: Nehmat Houssami, University of Sydney The study was endorsed by the European Society of Breast Imaging (EUSOBI) Steering Committee...

Here we describe the design and strength of a new synthetic late-early optimized (LEO) vaccinia virus (VACV) promoter used as a transcriptional regulator of GFP expression during modified vaccinia Ankara infection. In contrast to the described synthetic VACV promoter (pS), LEO induced significantly higher levels of GFP expression in vitro within the first hour after infection, which correlated ...

Direct comparison of high-resolution X-ray spectra of the active dMe star AD Leo, observed three times with Chandra, shows variability of key density-sensitive lines, possibly due to flaring activity. In particular, a significant long-duration enhancement of the coronal density is indicated by the Ne IX and Si XIII He-like triplets, and possibly also by density-sensitive Fe XXI line ratios. Sub...

Geophysical Fluid Dynamics (GFD) came of age in the 1950s and 1960s, with the mathematically inspired work of Charney, Lorenz, Stommel, Veronis and von Neumann, among others. In the last twenty years or so, mathematical, statistical and numerical developments for the Navier-Stokes equations and basic geophysical fluid dynamics models are stimulating a deepening and broadening of its central con...

The rapid growth of Internet-based applications pushes broadband satellite networks to carry on IP traffic. In previously proposed connectionless routing schemes in satellite networks, the metrics used to calculate the paths do not reflect the total delay a packet may experience. In this paper, a new Satellite Grouping and Routing Protocol (SGRP) is developed. In each snapshot period, SGRP divi...

Sporadic reports of Corynebacterium ulcerans infection in humans and animals have become increasingly common throughout the world. Between 2001 and 2006, five human cases, in addition to isolation of the bacterium from the carcasses of Orcinus orca and Panthera leo, were reported in Japan. While an isolate from P. leo generated only phospholipase D (PLD), the other isolates produced both PLD an...

Radial-velocity measurements and sine-curve fits to the orbital radial velocity variations are presented for ten close binary systems: OO Aql, CC Com, V345 Gem, XY Leo, AM Leo, V1010 Oph, V2612 Oph, XX Sex, W UMa, and XY UMa. Most of these binaries have been observed spectroscopically before, but our data are of higher quality and consistency than in the previous studies. While most of the stud...