Reduced intensity conditioning followed by allogeneic SCT (RIC-SCT) has recently emerged as promising new salvage option for children suffering from Langerhans cell histiocytosis (LCH) with risk organ involvement and failure to conventional therapy. We report on the posttransplant course of female toddler with high-risk LCH, who achieved complete remission after RIC-SCT, despite a posttransplan...

We report the case of a 37-year-old woman who presented with progressive renal dysfunction and proteinuria, in whom renal biopsy confirmed a diagnosis of AA amyloidosis. No evidence of chronic suppurative infection, connective tissue disease or malignancy was found. A past history of Langerhans cell histiocytosis (LCH) diagnosed in childhood was noted for which the patient had been successfully...

Laryngeal granuloma (LG) is a non-neoplastic lesion that mainly develops in the posterior vocal folds. It arises response to inappropriate use, and endotracheal intubation. Recently, it has been found coronavirus disease 2019 (COVID-19) also causes it. On other hand, lobular capillary hemangioma (LCH) non-LCH are two histopathological types of inflammatory hyperplasia lesions less common larynx...

Langerhans cell histiocytosis (LCH) is a rare disease in which Langerhans cells, which are bone marrow-derived antigen-presenting cells, proliferate in single or multiple organs. We successfully treated a patient with unifocal LCH of the mandible with malocclusion due to a severe pathological fracture, using reconstruction with a vascularised free bone.

BACKGROUND Histiocytic disorders are currently identified by their component cells. The non-Langerhans Cell Histiocytoses (non-LCH) are a group of disorders defined by the accumulation of histiocytes that do not meet the phenotypic criteria for the diagnosis of Langerhans cells (LCs). The non-LCH consist of a long list of diverse disorders which have been difficult to categorize. A conceptual w...

purpose : fine needle aspiration (fna) cytologic findings of langerhans cell histiocytosis (lch) have been well described, but using this method in the diagnosis of orbital lesions is a recent experience. we hereby report two cases of orbital bone lch diagnosed by fna that later was confirmed by routine h&e; histopathology and immunohistochemistry (ihc) methods. case reports : the first case wa...

The histiocytoses are a group of proliferative disorders of themonocyte-macrophage lineage that are neoplastic or reactive innature. Based on immunophenotyping and electron microscopy,two main groups have been recognized namely 1) Langerhanscell histiocytosis (LCH) and 2) non- Langerhans cell histiocytosis(non-LCH). In this study, a fairly rare disease of the non-LCHgroup, generalized eruptive ...

We read with great interest the recent review article on Langerhans cell histiocytosis (LCH) by Delprat and Aricò. As they mentioned, LCH is a rare disorder characterized by local accumulation of dysplastic Langerhans cells and a wide range of organ involvement. Although the precise pathophysiology remains unknown, recent findings suggest that LCH is likely to be a clonally expandingmyeloid neo...

Rosai-Dorfman disease (RDD) is a reactive multisystem histiocytosis that typically presents with cervical lymphadenopathy and systemic symptoms. Cutaneous involvement occurs in approximately 10% of cases, and 3% of cases are limited to the skin without nodal or other extranodal involvement. Langerhans cell histiocytosis (LCH) is a clonal histiocytosis with a wide spectrum of presentations rangi...