We developed a time-dependent diffusion model for analyzing the concentration profiles of low-molecular-weight tracers in the interendothelial clefts of the capillary wall that takes into account the three-dimensional time-dependent filling of the surrounding tissue space. The model provides a connecting link between two methods to investigate transvascular exchange: electron-microscopic experi...

The effects of cerium and lanthanum on the vegetative and reproductive growth of Arabidopsis thaliana were investigated. Addition of cerium (III) nitrate (0.5-50μM) and/or lanthanum nitrate (0.5-50μM) to the culture medium and the potting mix showed varied results. Pot trials were done with uniform conditions for light, water and temperature. Factors examined include root length, height, number...

Herein, we report on the preparation of liquid dimeric lanthanide(III)-containing compounds. Starting from design solids, demonstrate that by tuning anion and cation structures can lower melting points below room temperature, whilst maintaining structure. Magnetic measurements could establish spin-spin interactions neighboring lanthanide(III) ions in state at low temperatures, matched analogous...

Due to their high and variable coordination numbers leading to poorly predictable three-dimensional coordination spheres, the trivalent lanthanide metal ions are challenging molecular objects for introduction into thermotropic liquid crystals. Conversely, their predictive electronic, optical and magnetic metal-centred properties make them particularly attractive for being incorporated into swit...

Lanthanide metals are a particular class of magnetic materials in which the magnetic moments are carried mainly by the localized electrons of the 4f shell. They are frequently found in technically relevant systems, to achieve, e.g., high magnetic anisotropy. Magnetooptical methods in the x-ray range are well suited to study complex magnetic materials in an element-specific way. In this work, we...

Fluorescent microspheres have been demonstrated to be useful in a variety of biological applications. Fluorescent silica or polymer microspheres have been produced by incorporation of chromophores into the microspheres, which usually produces microspheres with nonuniform sizes and reduced fluorescence. Here we present a simple and straightforward method to produce silica microspheres with fluor...

The introduction of a 1,3-diacetylpyridine moiety, as an additional binding niche in a macrocyclic receptor ligand containing a conjugated, push–pull malonate functionality, leads to, in addition to the 1:1 binding stoichiometry, the equilibrium formation of multiple complexes, specifically 1:2, 2:1, and 3:1 ligand:metal complexes with lanthanide trications. Various binding modes elicit distinc...

A new peptide sequence (MB1) has been designed which, in the presence of a trivalent lanthanide ion, has been programmed to self-assemble to form a three stranded metallo-coiled coil, Ln(III)(MB1)3. The binding site has been incorporated into the hydrophobic core using natural amino acids, restricting water access to the lanthanide. The resulting terbium coiled coil displays luminescent propert...

Spectrally encoded fluorescent beads are an attractive platform for assay miniaturization and multiplexing in the biological sciences. Here, we synthesize hydrophilic PEG-acrylate polymer beads encoded with lanthanide nanophosphors using a fully automated microfluidic synthesis device. These beads are encoded by including varying amounts of two lanthanide nanophosphors relative to a third refer...