JUNE/JULY 2015 | PODIATRY MANAGEMENT 117 2). The origin of the syndesmosis procedure can be traced to the 1960s with the work of the Italian orthopedists Botteri and Castellana (Figure 3). In the 1970s, Florence orthopedists Pagella and Pierleoni described a case series of 145 osteodesis procedures. In 1999, there is a further article by the British orthopedist Irwin Cape, reporting on 75 inter...

The molecular mechanism of penicillin action is closely analogous to that of neostigmine. Both drugs react covalently with the active-site serine of their target enzymes. In both cases, the susceptible enzymes self-catalyze their inactivation by their respective drugs. Kinetic analysis of cholinesterase by Richard J. Kitz and Irwin B. Wilson helped to establish that concept. Neostigmine and pen...

Vol. 17, No. 3 2000 pp. 143–154 The adolescent developmental period has consistently been documented to be more strongly characterised by a propensity to engage in risk-taking behaviours than any other developmental period. Such behaviours have potentially dangerous or even fatal outcomes (e.g., Arnett, 1992; Flannery, Vazsonyi, & Rowe, 1996; Gonzalez et al., 1994; Gullone, Moore, Moss, & Boyd,...