Enantioselective esterification of ibuprofen was conducted to evaluate the enzyme activity and ees of lipase from Candida rugosa (CRL7) in ten conventional organic solvents and three ionic liquids. Different alcohols were tested for selecting the most suitable acyl acceptor due to the fact that the structure of alcohols (branch and length of carbon chains; location of -OH functional group) coul...

the ionic liquid, n,n,n,n-tetramethylguanidiniumtriflate (tmgtf) was found to be an efficient catalyst solvent for henry reaction between nitromethane and isatin derivatives to provide 3-hydroxy-3-(nitromethyl)indolin-2-one under mild conditions. the ionic liquid amenable to successive recycling without appreciable decrease in activity. synthesized compounds have been screened for their anti-di...

biodegradable nanoparticulate carriers, have important potential applications for administration of therapeutic molecules. chitosan based nanoparticles have attracted a lot of attention upon their biological properties such as biodegradability, biocom-patibility and bioadhesivity. the aim of the present investigation was to describe the synthesis and characterization of novel biodegradable nano...

Decreasing oil reserves, the need to reduce CO2 emissions and increasing energy demand are issues that are forcing scientists to search for new opportunities in the field of energy. As a result, biofuels have been considered as one possible solution to solve part of these challenges. This research is one small part of that effort. For both human and economic reasons the use of edible raw materi...

The prtnonation constant values of tryptophan were studied at 25 C. different ionic strengths. 0.1-1.0 moldm", and various ionic media of NaCIO, and N4N01, using a combination of spectrophotometrie andpotentiometric techniques. The general vend for the two protonation con Slant Vai net of tryptophan is in theorder of NaC104 > NaNO3 in different ionic media. The dependence of protonation constan...

Abstract The use of ionic flocculation is proposed to remove malachite green (MG), in this case, from water. A surfactant with the polluted solution and calcium added. surfactant-calcium reaction forms a precipitate, which aggregates into flocs on agitation. adsorb MG, can then be removed by centrifugation. Ionic was assessed varying parameters including: MG concentrations, electrolyte content,...

THE volume of many interphase nuclei and of condensed chromosomes has been considered to reflect the degree of condensation of a nucleoprotein gelwork [9]. Factors that may produce volume changes in isolated nuclei have therefore been explored in the hope of finding mechanisms that may be active in chromosomal condensation during cell division. At least three factors control nuclear volume in t...

INTRODUCTION Many drugs are unavailable in suitable oral paediatric dosage forms, and pharmacists often have to compound drugs to provide paediatric patients with an acceptable formulation in the right dose. Liquid formulations offer the advantage of dosing flexibility and ease of administration to young patients, but drug substances often show poor aqueous solubility. The objective of this wor...

The effect of strong electrolyte upon the activity of Vibrio cholerae neuraminidase (VC neuraminidase) toward the surface of intact cells and toward their isolated, purified sialolipid components, was studied in detail. A linear dependence of the logarithm of initial velocity on the square root of ionic strength was observed for purified GM8 over a concentration range of 0 to 0.05 M NaCl in 0.0...