نتایج جستجو برای: intravenous iron

تعداد نتایج: 218815  

Journal: :Pharmaceutical development and technology 2015
Monika Praschberger Carolin Cornelius Markus Schitegg Hans Goldenberg Barbara Scheiber-Mojdehkar Brigitte Sturm

CONTEXT Severe iron deficiency requires intravenous iron supplementation to replenish iron stores. Intravenous iron sucrose has been used for decades for the treatment of anemia. New generic iron sucrose products are now marketed for the use in several countries and there is an ongoing discussion about the safety and efficacy of iron sucrose similars. OBJECTIVE In this study, we compared the ...

2004
J. S. G. COX G. F. MOSS

SYNOPSIS A method is described for measuring the plasma unsaturated iron-binding capacity in the presence of very high concentrations of iron as iron-dextran. The procedure utilizes 59Fe to label the apotransferrin with subsequent separation of ionic iron from transferrin-bound iron on an ion exchange or Sephadex G.25 column. The unsaturated iron-binding capacity has been measured in rabbits an...

2013
Luke S.G.E. Howard Geoffrey M.J. Watson John Wharton Christopher J. Rhodes Kakit Chan Rajeshree Khengar Peter A. Robbins David G. Kiely Robin Condliffe Charlie A. Elliott Joanna Pepke-Zaba Karen Sheares Nicholas W. Morrell Rachel Davies Deborah Ashby J. Simon R. Gibbs Martin R. Wilkins

Our aim is to assess the safety and potential clinical benefit of intravenous iron (Ferinject) infusion in iron deficient patients with idiopathic pulmonary arterial hypertension (IPAH). Iron deficiency in the absence of anemia (1) is common in patients with IPAH; (2) is associated with inappropriately raised levels of hepcidin, the key regulator of iron homeostasis; and (3) correlates with dis...

2006
MASATAKA SHIRAKI

Adult-onset hypophosphatemic osteomalacia is very rare in well-developed countries [1]. The most likely diagnosis of such patients, if their diet contains enough vitamin D, is oncogenic or iatrogenic osteomalacia [2, 3]. Saccharated ferric oxide (SFO; [Fe(OH)3]m [C12H22O11]n) is an intravenous preparation indicated for patients with iron-deficiency anemia [4, 5]. Since its introduction into the...

2013
Alka Kriplani Reeta Mahey Biswa Bhusan Dash Vidushi Kulshreshta Nutan Agarwal Neerja Bhatla

BACKGROUND & OBJECTIVES Iron deficiency anaemia (IDA) is the most common nutritional deficiency in pregnancy. Prophylactic oral iron is recommended during pregnancy to meet the increased requirement. In India, women become pregnant with low baseline haemoglobin level resulting in high incidence of moderate to severe anaemia in pregnancy where oral iron therapy cannot meet the requirement. Pregn...

2017
Jolanta Malyszko Stefan D Anker

Iron deficiency anaemia is a global health problem that manifests as fatigue and poor physical endurance. Anaemia can be caused by dietary iron deficiency, blood loss or a combination of poor iron absorption and ineffective iron mobilization in patients with chronic disease. Nephrologists caring for patients with impaired renal function understand that iron treatment is necessary to provide ade...

2014
Amy Woods Laura A. Garvican-Lewis Philo U. Saunders Greg Lovell David Hughes Ruth Fazakerley Bev Anderson Christopher J. Gore Kevin G. Thompson Stephen E. Alway

PURPOSE To determine the effect of intravenous iron supplementation on performance, fatigue and overall mood in runners without clinical iron deficiency. METHODS Fourteen distance runners with serum ferritin 30-100 µg · L(-1) were randomly assigned to receive three blinded injections of intravenous ferric-carboxymaltose (2 ml, 100 mg, IRON) or normal saline (PLACEBO) over four weeks (weeks 0,...

Journal: :Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1996
F Sepandj K Jindal M West D Hirsch

BACKGROUND Iron deficiency is common in haemodialysis patients and adequate supplementation by the oral or parenteral route has been limited by drug side-effects, absorption, and cost. Intermittent doses of intravenous iron dextran complex are recommended in patients with inadequate iron stores despite maximal tolerated oral dose. We conducted a prospective study with economic analysis of a reg...

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