We report a case of disseminated microsporidiosis in a patient with multiple myeloma who had received an allogeneic stem cell transplant requiring substantial immunosuppression. The causative organism was identified as Tubulinosema acridophagus, confirming this genus of microsporidia as a novel human pathogen.

AKE: acrokeratoelastoidosis INTRODUCTION Acrokeratoelastoidosis (AKE), is a rare keratoderma characterized by small, round, skin-colored papules on the palms and soles. It was first described in 1952 by Brazilian dermatologist Oswaldo Costa and commonly presents before the age of 20. The primary etiology is unknown, and both autosomal dominant and sporadic forms have been reported in the dermat...

Correspondence to: Dr I Ormerod, Department of Neurology, Frenchay Hospital, Bristol, UK; ian.ormerod@ north-bristol.swest.nhs.uk _________________________ I t is not unusual to be asked for a neurological assessment of a patient with some form of immune suppression. Most patients will have an acquired disorder of the immune system and are the focus of this review (table 1). We shall not discus...

background: hormesis is defined as the bio-positive response of something which is bio-negative in high doses. in the present study, the effect of radiation hormesis was evaluated on the survival rate of immunosuppressed balb/c mice by cyclosporine a. materials and methods: we used 75 consanguine, male, balb/c mice in this experiment. the first group received technetium-99m (3700bq) and the sec...

Two cases of Strongyloides stercoralis hyperinfestation syndrome accompanied by Gram negative bacteraemia and meningitis were studied. Both occurred in non-immunosuppressed West Indian women.

an immunosuppressed man was admitted to hospital with diarrhea and a history of urinary tract infection. he was subjected to treatment with antibiotics. the patient died of putative severe sepsis. the etiological agent was a carbapenemase producing isolate of bacillus circulans with resistance to all prescribed antimicrobial agents.

A seven-year-old female spayed Schnauzer was presented with cutaneous ulcerated nodular lesions shortly after the beginning of an immunosuppressive treatment for immune-mediated hemolytic disease. Cytology was performed and a great number of neutrophils and banana-shaped organisms were observed. Biopsy showed a neutrophilic and histiocytic dermatitis and panniculitis with myriads of intralesion...

Merkel cell carcinoma (MCC) is a rare and aggressive cutaneous malignancy. The infectivity of Merkel cell polyomavirus (MCPyV), an apparent agent in MCC development, may be exacerbated with impaired immune responses. This paper reviews relevant data regarding the role of immunosuppression in the development of MCC and describes modes of immunodeficient states. Because of the inherently low inci...

BACKGROUND This is an update of the Cochrane review published in 2013, Issue 10.Immunosuppressed cancer patients are at increased risk of serious influenza-related complications. Guidelines, therefore, recommend influenza vaccination for these patients. However, data on vaccine effectiveness in this population are lacking, and the value of vaccination in this population remains unclear. OBJEC...

45-year-old man with acute lymphocytic leukemia (ALL) was found to have a solitary pulmonary nodule on routine chest radiograph. He had been diagnosed as having ALL three months previously and underwent induction chemotherapy which included vincristine, prednisone, cyclophosphamide, doxorubicm and intrathecal methotrexate. His leukemia was in remission and he had received no chemotherapy for on...