نتایج جستجو برای: immunostimulatory activity

تعداد نتایج: 1135910  

Journal: :International Journal of Nanomedicine 2006
Jihua Hao Marcin Kwissa Bali Pulendran Niren Murthy

This report presents a new and simple methodology for the synthesis of multicomponent peptide vaccines, named the peptide crosslinked micelles (PCMs). The PCMs are core shell micelles designed to deliver peptide antigens and immunostimulatory DNA to antigen-presenting cells (APCs). They are composed of immunostimulatory DNA, peptide antigen, and a thiopyridal derived poly(ethylene glycol)-polyl...

2011
Sophie Viaud Caroline Flament Mustapha Zoubir Patricia Pautier Axel LeCesne Vincent Ribrag Jean-Charles Soria Virginie Marty Philippe Vielh Caroline Robert Laurence Zitvogel

Low doses of the alkylating agent cyclophosphamide (CTX) mediate antiangiogenic and immunostimulatory effects, leading to potent tumoricidal activity in association with various immunotherapeutic strategies. Here, we show in rodents and cancer patients that CTX markedly promotes the differentiation of CD4þ T helper 17 (Th17) cells that can be recovered in both blood and tumor beds. However, CTX...

Journal: :Cancer research 2011
Sophie Viaud Caroline Flament Mustapha Zoubir Patricia Pautier Axel LeCesne Vincent Ribrag Jean-Charles Soria Virginie Marty Philippe Vielh Caroline Robert Nathalie Chaput Laurence Zitvogel

Low doses of the alkylating agent cyclophosphamide (CTX) mediate antiangiogenic and immunostimulatory effects, leading to potent tumoricidal activity in association with various immunotherapeutic strategies. Here, we show in rodents and cancer patients that CTX markedly promotes the differentiation of CD4(+) T helper 17 (Th17) cells that can be recovered in both blood and tumor beds. However, C...

Journal: :The Journal of Organic Chemistry 2010

Journal: :The Journal of antibiotics 1982
T Gotoh K Nakahara T Nishiura M Hashimoto T Kino Y Kuroda M Okuhara M Kohsaka H Aoki H Imanaka

An interesting immunoactive peptide, FK-156, has been isolated from the fermentation broth of Streptomyces olivaceogriseus sp. nov. and Streptomyces violaceus. The compound was purified by column chromatography with activated carbon, ion exchange Sephadex and cellulose powder. FK-156, obtained as white powder, exhibits a wide variety of immunostimulatory activity in vivo and in vitro with exper...

Journal: :Agriculture 2021

Despite the fact that humic substances (HS) have been frequently studied in relation to their effects on livestock health, studies influence egg production and quality, immunity, intestinal microbiota of laying hens are limited. In this study, 0.5% HS supplementation specific parameters eggshell mineral immune (relative expression IgA, IGF-2, MUC-2 gene cecum; activity phagocytes, percentage se...

Journal: :Journal of Dairy Science 1987

Journal: :Proceedings of the National Academy of Sciences 1994

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