نتایج جستجو برای: hirudin variant 3

تعداد نتایج: 1893080  

A. Alborzi M. H. Soodmand M. Rahmanian M. Zivdar R. Rahimi

The distillation process remains as the most common method ofseparation in chemical process industries. The energy used from this process accounts for an estimated 3% of <span style="font-size: 10pt; c...

Journal: :Agents and actions. Supplements 1992
M Siebeck M Spannagl H Hoffmann E Fink

Endotoxin shock and contact system activation were used to study effects of hirudin, antithrombin III, eglin C, aprotinin, and [Arg15]-aprotinin in anesthetized pigs. Alterations in the systemic and pulmonary circulation were in part prevented by administration of the inhibitors.

A. Parvareh, M. Rahimi R. Beigzadeh

"> Despite numerous studies of shell and helically coiled tube heat exchangers, a few investigations on the heat transfer and flow characteristic consider the geometrical <span style="font-size: 9pt; col...

J. Towfighi Sh. Masoumi

"> The effects of templating on the catalytic performance of SAPO-34 catalyst have been investigated in conversion of methanol to olefins. SAPO-34 <span style="font-size: 11pt; color: #000000; font-sty...

Journal: :Blood 2007
Jacob Sevastos Sean E Kennedy Darren R Davis Melissa Sam Philip W Peake John A Charlesworth Nigel Mackman Jonathan H Erlich

Ischemia/reperfusion (IR) injury is a leading cause of acute renal failure and an important contributor to allograft damage. Tissue factor (TF) is up-regulated during IR, and TF inhibition reduces renal injury. However, the underlying mechanisms by which TF contributes to injury have not been elucidated. We postulated that TF contributes to IR injury by production of coagulation proteases and s...

Journal: :Cancer research 2008
Liang Hu Jennifer M Roth Peter Brooks Joanna Luty Simon Karpatkin

Cathepsin D (CD) up-regulation has been associated with human malignancy and poor prognosis. Thrombin up-regulated CD mRNA and protein in eight tumor cell lines as well as in human umbilical vascular endothelial cells (HUVEC). Thrombin increased the secretion of CD by 3- to 8-fold and enhanced chemotaxis ( approximately 2-fold) in 4T1 murine mammary CA cells, which was completely inhibited with...

Objective(s): Organic cation transporter 3 (OCT3) as a high-capacity transporter contribute to the metabolism of metformin. The present study was conducted to determine the genotype frequencies of the variant OCT3-1233G>A (rs2292334) in patients with newly diagnosed type 2 diabetes (T2D) and its relationship with response to metformin. Materials and Methods: This study included 150 patients wit...

Journal: :The Journal of biological chemistry 1975
J S Rosenberg D L Beeler R D Rosenberg

In this communication we describe the first method for isolating human Factor V. The final product contains no other coagulation components as judged by functional assays and is physically homogeneous as shown by isofocusing gel electrophoresis. In addition, we present a means for obtaining intrinsically activated human Factor X-a. This preparation is usually homogeneous as judged by isofocusin...

2006
Jacob Sevastos Sean E. Kennedy Darren R. Davis Melissa Sam Philip W. Peake John A. Charlesworth Nigel Mackman Jonathan H. Erlich

Ischemia/reperfusion (IR) injury is a leading cause of acute renal failure and an important contributor to allograft damage. Tissue factor (TF) is up-regulated during IR, and TF inhibition reduces renal injury. However, the underlying mechanisms by which TF contributes to injury have not been elucidated. We postulated that TF contributes to IR injury by production of coagulation proteases and s...

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