When there is interest to study n chemicals using x dose levels each, factorial designs that require x(n) treatment groups have been put forward as one of the valuable statistical approaches for hazard assessment of chemical mixtures. Exemplary applications and cost-efficiency comparisons of full factorial designs and regular fractional factorial designs in toxicity studies can be found in Nesn...

Agricultural use of organochlorine pesticides (OCPs) increased during the twentieth century but many them have been progressively banned several decades after their introduction. Nevertheless, these lipophilic chemical compounds may persist in soils and sediments. From sediment deposits, it is possible to reconstruct chronology OCP releases relation former applications through time. long-term f...

Only 30% of all breast cancer can be explained by known risk factors. Increases in breast cancer incidence rates in Hawaii over the past few decades cannot be attributed solely to improvements in screening and detection. Avoidable environmental factors may contribute to a proportion of the unexplained cases. Emerging evidence on endocrine disruption suggests that environmental chemicals may pla...

QuEChERS stands for (Quick, Easy, Cheap, Effective, Rugged and Safe) and pronounced as (catchers) is a method that had been developed for multi-pesticide residue analyses in food. This study was conducted to investigate the efficacy of QuEChERS method for analyzing the organochlorine pesticides residues in cow's milk. Twenty organochlorine pesticide namely (Benzene, 1,3,5-trichloro, Tetrachloro...

Abstract Honey is a suitable matrix for the evaluation of environmental contaminants including organochlorine insecticides. The present study was conducted to evaluate residues fifteen insecticides in honey samples unifloral and multifloral origins from Dir, Pakistan. (5 g each) were extracted with GC grade organic solvents then subjected Rotary Evaporator till dryness. extracts mixed n-Hexane ...

Brazil has experienced a rise in the use of agrochemicals recent years, representing potential threat to nearby ecosystems. The Volta Grande Reservoir (Minas Gerais/São Paulo, Brazil) about 87% its area surrounded by agricultural systems, and many compounds used agriculture end up being carried into water bodies. Given ecological risk, our purpose was assess pesticides reservoir. We collected s...