............................................................................................................................. i LIST OF ORIGINAL PUBLICATIONS ................................................................................ ii CONTENTS ............................................................................................................................iii ABBREVIATIONS........

This is the official guideline endorsed by the specialty associations involved in the care of head and neck cancer patients in the UK. This paper summarises the role of chemotherapy in head and neck cancer management, recent advances and what the future holds for this modality.

.......................................................................................iii ACKNOWLEDGEMENTS......................................................................v LIST OF TABLES................................................................................viii LIST OF FIGURES...............................................................................ix CHAPTER

Standard approach to the treatment of head and neck cancer include surgery, chemotherapy, and radiation. More recently, dramatic increases in our knowledge of the molecular and genetic basis of cancer combined with advances in technology have resulted in novel molecular therapies for this disease. In particular, gene therapy, which involves the transfer of genetic material to cells to produce a...