Ototoxic models of animal represent an elemental tool in basic otological research. In the present study, using guinea pigs we compared cochlear lesions mediated via cisplatin applied in terms of two regimens: consecutive application alone and in combination with furosemide. The influences of furosemide alone were also assessed; it was observed to result in temporary hearing loss and reversible...

Background: Enterococcus, which comprises of gram positive organism acts as opportunistic pathogens which has their natural habitat in genital tract, gut and oral cavity. Resistance to wide variety of antibiotics has made enterococcus one of the important cause for nosocomial infection. Emergence of aminoglycoside resistance has made it a feared pathogen. Objective: Objective was to isolate, sp...

A total of 100 patients suffering from CSOM were randomly selected from department of Otorhinolaryngology , Narayana Hospital, Narayana Medical College, Nellore. The ear discharge was collected and subjected to direct smear, aerobic culture and sensitivity. Direct smear examination and culture was positive in 93% of cases. Pseudomonas aeruginosa was the most predominant species in 40% of cases ...

There is an increasing prevalence of urinary tract infection (UTI) caused by multiresistant gram-negative enteric bacilli such as extended-spectrum beta-lactamase as well as Gram-positive enterococci whose vancomycin-resistance can be as high as 25%. We report on a 68-year-old Caucasian female with a UTI caused by a vancomycin-resistant Enterococcus faecium, only tested to be susceptible to gen...

Listeria monocytogenes (LM) is an aerobic, motile, intracellular gram-positive bacterium. Most invasive systemic infections caused by LM are commonly seen in patients at both extremes of age, during pregnancy or in immunocompromised hosts. Common clinical manifestations of LM infection in immunocompromised adults are bacteremia, infections of central nervous system, such as meningitis, and self...