Warren, Richard A., Peyman Golshani, and Edward G. Jones. or seizurelike activity do not occur in human infants (Aicardi GABAB-receptor-mediated inhibition in developing mouse ventral 1994) or in infant animal models (Marescaux et al. 1992b). posterior thalamic nucleus. J. Neurophysiol. 78: 549–553, 1997. This may be related to immaturity of the membrane and Inhibitory postsynaptic potentials (...

Though we are approaching the end of second wave COVID pandemic, still unrevealing various presentation this viral infection can result in. There few cases reported to have anti NMDA autoimmune encephalitis associated with COVID-19 or MIS-C. Here reporting one its variants that was anti-GABAB receptor infection. We a 9 years old female child who known case seizure disorder and on regular medica...

the present work was performed to show the possible interaction of gab a, and gabab receptors in catalepsy. the following results were obtained: 1- muscimol (mus), a gabaa agonist, induced catalepsy. this effect was dose-dependent. baclofen (bac), a gabab agonist, had no effect in this respect. 2- catalepsy induced by muscimol was potentiated by pretreatment of animals with bicuculline (bic), a...

PCPGABA, injected into the cisterna magna, significantly stimulated gastric acid secretion in the perfused rat stomach preparation. This secretagogue action was dose-dependent (0.5-2 micrograms/rat). The peak response occurred within 60 min and lasted up to 100 min. The secretagogue action by PCPGABA was completely reduced by truncal vagotomy. Intracisternal injection of 5-aminovaleric acid, a ...

The compounds CGP7930 [2,6-Di-tert-butyl-4-(3-hydroxy-2,2dimethyl-propyl)-phenol] and its close analog CGP13501 were identified as positive modulators of -aminobutyric acidB (GABAB) receptor function. They potentiate GABA-stimulated guanosine 5 -O-(3-[S]thiotriphosphate) (GTP [S]) binding to membranes from a GABAB(1b/2) expressing Chinese hamster ovary (CHO) cell line at low micromolar concentr...

introduction: the present study investigated the interactive effect of gabab receptors and extremely low frequency electromagnetic field (elf-emf) on foot shock-induced aggression in rats. methods: fifty adult male rats were randomly assigned into 10 groups. groups 2, 4, 6, 8 and 10 were exposed to 50 hz, 500 µt elf-emf for 30 days 8h per day while the remaining groups (1, 3, 5, 7 and 9) were s...

the objective of the present investigation was to assess the possible involvement ofgabaergic mechanism in analgesic effect of aqueous extract of origanum vulgare (org)in a rat model of acute pain test. sixty-three anaesthetized male wistar rats (200-250 g) werecannulated into the left ventricle. five to seven days after the recovery from surgery, org extractwas intraventricularly injected at d...